Angiogensis and desmoplasia of liver cancer derived from hepatic progenitor cell: imaging analysis

肝祖细胞来源的肝癌的血管生成和结缔组织形成：成像分析

• 批准号: 22591343
• 负责人: ASAYAMA Yoshiki
• 金额: $ 1.83万
• 依托单位: Kyushu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22591343/
• 关键词: 肝幹細胞; 細胆管癌; 肝細胞癌; 胆管細胞癌; CT; MRI; 線維化; 脂肪化; 肝腫瘤; MRI(核磁気共鳴画像); Gd-EOB-DTPA

(1)Cholangiolocellular carcinoma has the dual imaging characteristics of hepatocellular carcinoma and cholangiocarcinoma. (2)Gadoxetic acid-enhanced MRI was found useful for differentiating intrahepatic cholangiocarcioma and poorly differentiated hepatocellular carcinoma, especially during the dynamic late phase.(3)The frequency of fatty change in pHCC, as well as in wHCC, is significantly higher than that of mHCC. One possible mechanism of it is intratumoral decreased arterial flow

（1）胆管细胞癌具有肝细胞癌和胆管细胞癌的双重影像学特征。（2）肝内胆管癌和低分化肝细胞癌的MRI增强扫描，尤其是动态晚期增强扫描，对鉴别诊断有一定的价值。（3）pHCC和wHCC中脂肪样改变的频率显著高于mHCC。其可能机制之一是肿瘤内动脉血流减少

项目成果

Uptake of Gd-EOB-DTPA by hepatocellular carcinoma: Radiologic-pathologic correlation with special reference to bile production

• DOI: 10.1016/j.ejrad.2010.10.032
• 发表时间: 2011-12-01
• 期刊: EUROPEAN JOURNAL OF RADIOLOGY
• 影响因子: 3.3
• 作者: Asayama, Yoshiki;Tajima, Tsuyoshi;Honda, Hiroshi
• 通讯作者: Honda, Hiroshi

Fatty change in poorly differentiated hepatocellular carcinoma: possible mechanism in relation todecreased arterial flow

低分化肝细胞癌中的脂肪变化：与动脉血流减少相关的可能机制

• 发表时间: 2012
• 作者: Asayama Y;et al.;浅山良樹ら
• 通讯作者: 浅山良樹ら

Distinguish intrahepatic cholangiocarcinoma from poorly differentiated hepatocellular carcinoma using gadoxetic acid-enhanced MRI

使用钆塞酸增强 MRI 区分肝内胆管癌和低分化肝细胞癌

• 发表时间: 2012
• 作者: Asayama Y;et al.;浅山良樹ら;浅山良樹ら
• 通讯作者: 浅山良樹ら

Hypovascular hepatic nodule showing hypointensity in the hepatobiliary phase of gadoxetic acid-enhanced MRI in patients with chronic liver disease: Prediction of malignant transformation

• DOI: 10.1016/j.ejrad.2012.05.008
• 发表时间: 2012-11-01
• 期刊: EUROPEAN JOURNAL OF RADIOLOGY
• 影响因子: 3.3
• 作者: Takayama, Yukihisa;Nishie, Akihiro;Honda, Hiroshi
• 通讯作者: Honda, Hiroshi

動脈性消化管出血に対する動脈塞栓術の有用性についての検討

动脉栓塞治疗消化道动脉出血的有效性研究

• 发表时间: 2011
• 作者: Asayama Y;et al.;浅山良樹ら;浅山良樹ら;浅山良樹;浅山良樹;浅山良樹ら
• 通讯作者: 浅山良樹ら