Detection of free intraperitoneal cancer cells and chemosensitivity testing using gene expression analysis for gastric cancer patients
Detection of free intraperitoneal cancer cells and chemosensitivity testing using gene expression analysis for gastric cancer patients
批准号:
22591473
负责人:
ITO Seiji
金额:
$3.08万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
This study aimed at integrated development of the genetic detection of peritoneal micrometastases and effective therapy based on biological characteristics of peritoneal micrometastases. Microarray analysis was performed for the cell lines with low CEA expression and new marker genes were identified. The predicting model for peritoneal metastasis was constructed. Both sensitive and resistant cell lines for paclitaxel were establishedandgene expression profiling was compared with parent cell line. The selected genes were validated by clinical samples andidentified as paclitaxel-resistance related genes.
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胃癌腹膜再発予測モデルを用いたmultiple genetic markerの意義の検討
使用胃癌腹膜复发预测模型检查多种遗传标记的意义
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Fischera A, Zoccali M, Kono T, 伊藤誠二]
通讯作者:
伊藤誠二
Development of rapid isolation device for circulating tumor cells (CTCs) using size-based filtrationmethod and its application for single cell gene expression analysis
基于尺寸的过滤方法开发循环肿瘤细胞(CTC)快速分离装置及其在单细胞基因表达分析中的应用
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[YusaA,MasudaT, Yamamoto S, Niimi M, Douke H, Okochi M, Toneri M, Ito S, Honda H, Arai F, Nakanishi H.]
通讯作者:
Nakanishi H.
胃癌腹膜転移に対するPTXの新規感受性予測因子の網羅的探索
全面寻找PTX对胃癌腹膜转移的新型敏感性预测因子
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Kinouchi M, et al, 村上弘城]
通讯作者:
村上弘城
"In Vivo Imaging" Methods and Protocols
“体内成像”方法和方案
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Nakanishi, H, Ito S]
通讯作者:
Ito S
"胃癌腹腔内微小転移のメカリズムとその検出"臨床外科
《胃癌腹腔微转移机制及其检测》临床外科
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[中西速夫, 舎人誠, 村上弘城, 伊藤友一, 三澤一成, 伊藤誠二]
通讯作者:
伊藤誠二
共 19 条
Isolation of circulating tumor cells (CTC) and peritoneal tumor cells (PTC) by cytology-based filtration platform and its application to monitoring therapeutic effect
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批准号:16K10524
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
-
财政年份:2016
-
负责人:ITO Seiji
-
依托单位:
3D analysis of functional neural network of sensory input and output in the spinal cord by use of transgenic mice expressing fluorescent proteins
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批准号:25293137
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.06万
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财政年份:2013
-
负责人:ITO Seiji
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依托单位:
Detection of free intraperitoneal/circulating tumor cells and possible selection of chemosensitive patientsfor neoadjuvant chemotherapy using gene expression analysis for gastric cancer.
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批准号:25462043
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.24万
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财政年份:2013
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负责人:ITO Seiji
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依托单位:
Study on gate control theory of pain by two-photon microsucopy using gene-engineered mice.
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批准号:23659322
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
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财政年份:2011
-
负责人:ITO Seiji
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依托单位:
Intracellular signal transduction of chronic pain in the spinal cord and tempospatial analysis of intercellular bioactive substances
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批准号:22390063
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.98万
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财政年份:2010
-
负责人:ITO Seiji
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依托单位:
Systematic study on the mechanism of generation, maintenance and recognition of neuropathic pain, a model of neural plasticity
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批准号:17109005
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项目类别:Grant-in-Aid for Scientific Research (S)
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资助金额:$71.97万
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财政年份:2005
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负责人:ITO Seiji
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依托单位:
Functional analysis of protein complex involved in neuropathic pain by proteomics
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批准号:15390109
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$8.64万
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财政年份:2003
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负责人:ITO Seiji
-
依托单位:
Studies on neural regeneration and reorganization of neural circuits in neuropathic pain
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批准号:13470039
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$6.21万
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财政年份:2001
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负责人:ITO Seiji
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依托单位:
Cloning of nocistatin receptor and development of new aanalgesics
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批准号:11558093
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$6.34万
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财政年份:1999
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负责人:ITO Seiji
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依托单位:
Elucidation of mechanism for induction of pain with knockout mice
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批准号:11470044
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$2.69万
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财政年份:1999
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负责人:ITO Seiji
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依托单位:
Elucidation of Mechanism of Pain Transmission by Gene Targeting
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批准号:09480168
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.22万
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财政年份:1997
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负责人:ITO Seiji
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依托单位:
Elucidation of physiological roles of prostaglandin F_<2alpha> and its regulatory mechanism in the reproductive system
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批准号:06454171
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.54万
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财政年份:1994
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负责人:ITO Seiji
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依托单位:
Cloning of prostaglandin E receptor cDNAs and molecular mechanisms of activation
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批准号:04670170
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.41万
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财政年份:1992
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负责人:ITO Seiji
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依托单位:
Biochemical Characterization and Cloning of Prostaglanoin D_2 Recoptor
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批准号:02670118
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项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.6万
-
财政年份:1990
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负责人:ITO Seiji
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依托单位:
Purification and Characterization of Prostaglandin E Receptor
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批准号:63570125
-
项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.22万
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财政年份:1988
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负责人:ITO Seiji
-
依托单位:
海外基金