课题基金 / 基金详情

Development of a novel therapy for malignant glioma based on theSNIP-microarray analysis and Glioma Cancer Stem cell theory

Development of a novel therapy for malignant glioma based on theSNIP-microarray analysis and Glioma Cancer Stem cell theory
基于 SNIP 微阵列分析和神经胶质瘤干细胞理论开发恶性神经胶质瘤新疗法
批准号:
22591616
负责人:
NAKAMURA Hideo
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012

项目摘要

项目成果

NAKAMURA Hideo的其他基金

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中文摘要
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英文摘要
We focused on the biological property of glioma cancer stem cellto investigate the mechanism of drug resistance in malignant glioma. We could maintainthe property of stem cell by culturing under the special condition and did an experimentof the biology of drug resistance. We investigated the genomic profiles of glioma cellsusing SNIP-microarray and found that genetic alterations such as p53 reduced thesensitivity of drugs. While, we also found that differentiation of the glioma cellscontributed to the sensitivity of drugs
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会议论文
ブレインナーシング 2010 夏季増刊号 神経膠腫
脑护理 2010 年夏季特刊胶质瘤
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [中村英夫, 倉津純一]
通讯作者: 倉津純一
脳神経外科速報
神经外科通报
DOI: --
发表时间: 2016
期刊:
影响因子: --
作者: [Watanabe, C. E. and Novotny, J., 高橋英海, 西悠太,林孝茂,姫野由香,牛苗,大堂麻里香,安藤万葉, 山尾幸広,國枝武治,松本理器]
通讯作者: 山尾幸広,國枝武治,松本理器
DOI: 10.1258/ar.2012.120525
发表时间: 2013-03-01
期刊: ACTA RADIOLOGICA
影响因子: 1.3
作者: [Nakamura, Hideo, Murakami, Ryuji, Yamashita, Yasuyuki]
通讯作者: Yamashita, Yasuyuki
膠芽腫症例における摘出度と再発形式の検討
胶质母细胞瘤切除程度及复发类型的检查
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [嵯峨伊佐子, Sampetrean Oltea, 大須賀覚, 大西伸幸, 杉原英志, 大久保淳, 柴尾俊輔, 吉田一成, 佐谷秀行, 中村英夫]
通讯作者: 中村英夫
39
    Development of capacitively-coupled multi-channel surface EMG interface
    • 批准号:
      21700587
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.83万
    • 财政年份:
      2009
    • 负责人:
      NAKAMURA Hideo
    • 依托单位:
    Development of computer interface based on neuromuscular system activity signal on multi-channel surface electromyograms
    • 批准号:
      19700453
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.34万
    • 财政年份:
      2007
    • 负责人:
      NAKAMURA Hideo
    • 依托单位:
    Investigation for the mechanism of the therapeutic resistance in central nervous system germ cell tumors based on the genetic & biological analysis
    • 批准号:
      19591689
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.83万
    • 财政年份:
      2007
    • 负责人:
      NAKAMURA Hideo
    • 依托单位:
    Functional analysis of malignant brain tumor related gene <h-neu> and development of a novel molecular tageting therapy based on the h-neu gene function
    • 批准号:
      17591520
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.92万
    • 财政年份:
      2005
    • 负责人:
      NAKAMURA Hideo
    • 依托单位: