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Liver regeneration by means of partial splenic embolization(PSE)-associated with autologous bone marrow cell transplantation-

Liver regeneration by means of partial splenic embolization(PSE)-associated with autologous bone marrow cell transplantation-
通过部分脾栓塞(PSE)与自体骨髓细胞移植相关的肝再生
批准号:
22791215
负责人:
YAMAMOTO Akira
金额:
$2.5万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
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项目摘要

项目成果

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中文摘要
翻译
在这项研究中,我们制作了一个慢性肝损伤兔模型。我们证实有明显的肝纤维化。我们获得了充足的兔骨髓干细胞,纯化后的骨髓中含有间充质干细胞。对照组置入导管,灌注生理盐水,栓塞脾动脉,灌注干细胞,栓塞脾动脉,灌注骨髓细胞。我们证实骨髓加PSE组血清胆红素有改善;不管有多少兔子死了。这可能是慢性肝损伤模型兔的过度应激。
英文摘要
In this study, we were able to make a rabbit model with chronic liver damage. We confirmed significant fibrosis of the liver. We obtained adequate bone marrow stem cells of rabbit and purified bone marrow contains mesenchymal stem cells. We inserted catheter and infused normal saline to the rabbit in the control group, embolized splenic artery, infused stem cells, and embolized splenic artery and infused bone marrow cells. We confirmed the improvement of the serum bilirubin in the bone marrow plus PSE group ; however many rabbits died. This was considered to be over stress to the rabbit with chronic liver damage model.
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Polymerization characteristics control using the modality laserspeckle analysis
  • 批准号:
    23792189
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
  • 资助金额:
    $1.58万
  • 财政年份:
    2011
  • 负责人:
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  • 依托单位:
Brain atlas using ultra high resolution DTI and SWI
  • 批准号:
    23591765
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
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  • 财政年份:
    2011
  • 负责人:
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Development of novel transdermal delivery formulation of incretin using biodegradable microneedle arrays
  • 批准号:
    22590155
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.0万
  • 财政年份:
    2010
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Development of Postmortem Diagnostic Imaging Method Using 3-T MRI
  • 批准号:
    21200020
  • 项目类别:
    Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
  • 资助金额:
    $19.05万
  • 财政年份:
    2009
  • 负责人:
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