Liver regeneration by means of partial splenic embolization(PSE)-associated with autologous bone marrow cell transplantation-
Liver regeneration by means of partial splenic embolization(PSE)-associated with autologous bone marrow cell transplantation-
批准号:
22791215
负责人:
YAMAMOTO Akira
金额:
$2.5万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
In this study, we were able to make a rabbit model with chronic liver damage. We confirmed significant fibrosis of the liver. We obtained adequate bone marrow stem cells of rabbit and purified bone marrow contains mesenchymal stem cells. We inserted catheter and infused normal saline to the rabbit in the control group, embolized splenic artery, infused stem cells, and embolized splenic artery and infused bone marrow cells. We confirmed the improvement of the serum bilirubin in the bone marrow plus PSE group ; however many rabbits died. This was considered to be over stress to the rabbit with chronic liver damage model.
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BESS Experiment to Search for Cosmic Ray Antiparticle
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海外基金