Neural mechanisms underlying the improvement of blood flow in the jaw muscles evoked by vagal afferent stimulation

迷走神经传入刺激引起下颌肌肉血流改善的神经机制

• 批准号: 22791796
• 负责人: ISHII Hisayoshi
• 金额: $ 1.16万
• 依托单位: Health Sciences University of Hokkaido
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22791796/
• 关键词: 副交感神経; 血管拡張反応; 迷走神経; 孤束核; GABA受容体; 咀嚼筋; 中枢神経; 中枢神経系; 求心性刺激; 末梢性神経機構

The present study examined the neural mechanisms underlying the improvement of blood flow in the masseter muscle evoked by vagal afferent stimulation. Our results indicate that cervical vagus nerve stimulation elicits the increase of blood flow in the rat masseter muscle mediated by vagal-parasympathetic reflex vasodilatation, and suggest that nucleus of the solitary tract play an important role in the blood flow increase in the jaw muscles.

本研究探讨了迷走神经传入刺激改善咬肌血流量的神经机制。结果表明，刺激颈迷走神经引起大鼠咬肌血流量增加，这是由迷走神经-副交感神经反射血管扩张介导的，提示孤束核在颌肌血流量增加中起重要作用。

项目成果

Involvement of vagal visceral inputs to the nucleus of the solitary tractin parasympathetic reflex vasodilatation in the rat masseter muscle

迷走神经内脏输入对大鼠咬肌孤束核副交感神经反射性血管舒张的影响

• 发表时间: 2010
• 作者: Ishii H;Niioka T and Izumi H.
• 通讯作者: Niioka T and Izumi H.

レーザースペックル血流計による血流動態のイメージング解析

利用激光散斑血流计进行血流动力学成像分析

• 发表时间: 2011
• 期刊: 北医療大歯誌(総説)
• 作者: 新岡丈治;石井久淑;和泉博之
• 通讯作者: 和泉博之

GABAB receptors in the NTS mediate the inhibitory effect of trigeminal nociceptive inputs on parasympathetic reflex vasodilation in the rat masseter muscle

• DOI: 10.1152/ajpregu.00569.2011
• 发表时间: 2012-03-01
• 期刊: AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
• 影响因子: 2.8
• 作者: Ishii, Hisayoshi;Izumi, Hiroshi
• 通讯作者: Izumi, Hiroshi