Research for the regeneration of periodontal tissue using periodontal ligament-derived hemangioblasts-like cells
Research for the regeneration of periodontal tissue using periodontal ligament-derived hemangioblasts-like cells
批准号:
22791936
负责人:
TAKAHASHI Noriko
金额:
$2.5万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
In this study, we focused on the CDX2 gene such as a key gene that induces into hematopoietic stem cells. PDL cells over-expressing CDX2 gene were observed to differentiate into hematopoietic stem-like cells. In addition, we attempted to isolateof hematopoietic stem cells from mouse bone marrow. As a result, the hematopoietic stem cells of Sca-1, CD34, CD45-positive were obtained. These hematopoietic stem cells adhere to type IV collagen, but it does not adhere to type I collagen. Furthermore, hematopoietic stem cells proliferated vigorously by a feeder of mesenchymal stem cells. Elucidation of the induction of angiogenesis is expected by using these cells.
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間葉系幹細胞由来サイトカイン様ペプチドSCRG1は破骨細胞分化を抑制する
间充质干细胞衍生的细胞因子样肽 SCRG1 抑制破骨细胞分化
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[西原一秀, 松山孝司, 松井竜太郎, 野添悦郎, 中村典史, 齋藤大嗣, 横田潤, 西原一秀, 青松恵美子]
通讯作者:
青松恵美子
Dental pulp cells derived from permanent teeth express higher levels of R-cadher in than do deciduous teeth : Implications of the correlation between R-cadherin expression and restriction of multipotency in mesenchymal stem cells
恒牙衍生的牙髓细胞比乳牙表达更高水平的 R-cadher :R-cadherin 表达与间充质干细胞多能性限制之间相关性的意义
DOI:
10.1016/j.archoralbio.2011.07.013
发表时间:
2011
期刊:
Archives of Oral Biology
影响因子:
3
作者:
[Yoshihiro Uesawa, Masami Kawase, Mariko Ishihara, Hiroshi Sakagami,, Takahashi N]
通讯作者:
Takahashi N
TGF-β-induced smooth muscle cell differentiation of ligament-derived endothelial progenitor-like cells
TGF-β诱导韧带源性内皮祖细胞样平滑肌细胞分化
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Anpo M, Shirayama K, Tsutsui T., 長谷川智一, 照井優一,佐藤康太郎,栗山壮一,国井淳,堀田康弘,宮崎隆, 大久保直登]
通讯作者:
大久保直登
TGF-βを介したヒト口腔扁平上皮癌細胞HSC-4における上皮間葉転換について
TGF-β介导的人口腔鳞状细胞癌细胞HSC-4的上皮-间质转化
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[Kazuhide Nishihara, Toshiro Kibe, Takao Fuchigami, Takako Okawachi, Etsuro Nozoe, Norifumi Nakamura, 照井優一,佐藤康太郎,栗山壮一,国井 淳,堀田康弘,宮崎 隆, 斎藤大嗣]
通讯作者:
斎藤大嗣
ヒト口腔扁平上皮癌細胞におけるTGF-βによる上皮間葉転換について
TGF-β诱导人口腔鳞状细胞癌细胞的上皮-间质转化
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[田中荘子, 西原一秀, 野添悦郎, 新崎 章, 中村典史, 齋藤大嗣]
通讯作者:
齋藤大嗣
共 17 条
Elucidation of the mechanism of nuclear signal transduction by retinoic acid based on new insight and its applications
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批准号:22590074
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2010
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负责人:TAKAHASHI Noriko
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依托单位:
Elucidation of retinoic acid mechanism of action mediated through non-retinoic acid nuclear receptors and its applications
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批准号:19590085
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2007
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负责人:TAKAHASHI Noriko
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依托单位:
Analysis of endocrine pancreas using two-photon excitation imaging
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批准号:19590204
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2007
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负责人:TAKAHASHI Noriko
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依托单位:
Study on development of drugs for cerebral nerve by new approach
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批准号:15590072
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.11万
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财政年份:2003
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负责人:TAKAHASHI Noriko
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依托单位:
Study on development of drugs for endocrine and metabolic disorders based on properties of new enzyme
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批准号:12672127
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.73万
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财政年份:2000
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负责人:TAKAHASHI Noriko
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依托单位:
Study for The Development of Anti-cancer Drug Based on A New Mechanism of Actions
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批准号:10672065
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.6万
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财政年份:1998
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负责人:TAKAHASHI Noriko
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依托单位:
Polymorphism of oligosaccharide structure in glycoconjugaates
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批准号:01304030
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项目类别:Grant-in-Aid for Co-operative Research (A)
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资助金额:$10.24万
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财政年份:1989
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负责人:TAKAHASHI Noriko
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依托单位:
Oligosaccharide Structure and Biological Activity of Erythropoietin
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批准号:63480504
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$0.58万
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财政年份:1988
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负责人:TAKAHASHI Noriko
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依托单位:
海外基金