Elucidation of mechanism of developing the periodontitis at the host-parasite interface

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Analyzing the subgingival plaque and the gingival tissues samples, it was elucidated that the deeper the periodontal pocket the patient has, the larger the amounts of the anaerobic bacteria and the inflammatory cytokines were detected. It is possible to evaluate the profiles of the clinical conditions of periodontitis in the initial preparation stage from the views of microbiology and immunology. In the future, we will be able to provide the effective treatment for the periodontitis patient by profiling the amounts of the anaerobic bacteria and the inflammatory cytokines.