Production of value-added chemicals from lignin-related materials using biotechnological process

利用生物技术工艺从木质素相关材料生产增值化学品

• 批准号: 22780080
• 负责人: HABE Hiroshi
• 金额: $ 2.41万
• 依托单位: National Institute of Advanced Industrial Science and Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22780080/
• 关键词: バイオリファイナリー; ジメチルスルフィド; 硫酸飢餓応答; 含硫アミノ酸; メチオニン

Sulfur is an essential element for bacterial growth and is normally acquired through the assimilation of inorganic sulfate. However, in some environments, sulfate may not be freely available because inorganic sulfate constitutes less than 5% of the total sulfur in the environments. Thus, several bacterial species have evolved the ability to use a wide variety of organosulfur compounds such as dimethyl sulfide(DMS), and both the genes and enzymes involved in the use of such compounds have been studied in detail. We tried to develop a method for production of useful chemicals such as sulfur amino acids from biomass-derived DMS using such sulfur-starvation-induced enzymes.

硫是细菌生长的必需元素，通常通过无机硫酸盐的同化获得。然而，在某些环境中，硫酸盐可能无法自由获得，因为无机硫酸盐占环境中总硫的不到5%。因此，几种细菌物种已经进化出使用多种有机硫化合物如二甲基硫醚（DMS）的能力，并且已经详细研究了使用此类化合物所涉及的基因和酶。我们试图开发一种使用这种硫饥饿诱导的酶从生物质来源的DMS生产有用的化学品如含硫氨基酸的方法。