The role of stress proteins in gastrointestinal and respiratory diseases
The role of stress proteins in gastrointestinal and respiratory diseases
批准号:
22790072
负责人:
TANAKA Kenichiro
金额:
$2.5万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
Idiopathic pulmonary fibrosis(IPF) is thought to involve inflammatory infiltration of leukocytes, lung injury induced by reactive oxygen species(ROS), in particular superoxide anion, and fibrosis(collagen deposition). Intravenous administration of PC-SOD suppressed the bleomycin-induced increase in the number of leukocytes in bronchoalveolar lavage fluid. Bleomycin-induced collagen deposition and increased hydroxyproline levels in the lung were also suppressed in animals treated with PC-SOD, suggesting that PC-SOD suppresses bleomycin-induced pulmonary fibrosis.
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DOI:
10.1124/jpet.111.179051
发表时间:
2011-09-01
期刊:
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
影响因子:
3.5
作者:
[Tanaka, Ken-Ichiro, Tanaka, Yuta, Mizushima, Tohru]
通讯作者:
Mizushima, Tohru
Protective effect of β-(1,3 → 1,6)-d-glucan against irritant-induced gastric lesions
β-(1,3 → 1,6)-d-葡聚糖对刺激性胃损伤的保护作用
DOI:
--
发表时间:
2011
期刊:
British Journal of Nutrition
影响因子:
3.6
作者:
[Ken, Yuta Tanaka, Toshio Suzuki, T. Mizushima]
通讯作者:
T. Mizushima
Therapeutic effect of lecithinized superoxide dismutase (PC-SOD) on bleomycin-induced pulmonary fibrosis.
卵磷脂化超氧化物歧化酶(PC-SOD)对博来霉素诱导的肺纤维化的治疗作用。
DOI:
--
发表时间:
2010
期刊:
Am J Physiol Lung Cell Mol Physiol.
影响因子:
--
作者:
[Tanaka KI., Ishihara T., Azuma A., Kudoh S., Ebina M., Nukiwa T., Sugiyama Y., Tasaka Y., Namba T., Ishihara T., Sato K., Mizushima Y., Mizushima T.]
通讯作者:
Mizushima T.
DOI:
10.1016/j.bcp.2011.06.030
发表时间:
2011-10-01
期刊:
BIOCHEMICAL PHARMACOLOGY
影响因子:
5.8
作者:
[Ishihara, Tomoaki, Suemasu, Shintaro, Mizushima, Tohru]
通讯作者:
Mizushima, Tohru
Prevention of ultraviolet B radiation-induced epidermal damage by expression of heat shock protein 70.
通过表达热休克蛋白70来预防紫外线B辐射引起的表皮损伤。
DOI:
--
发表时间:
2010
期刊:
J Biol Chem 285
影响因子:
--
作者:
[Matsuda M, Hoshino T, Yamashita Y, Tanaka KI, Maji D, Sato K, Adachi H, Sobue G, Ihn H, Funasaka Y, Mizushima T.]
通讯作者:
Mizushima T.
共 6 条
Psychological research on the developmental metamorphosis of leader identity
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批准号:24653167
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$1.0万
-
财政年份:2012
-
负责人:TANAKA Kenichiro
-
依托单位:
Regulation of inflammation by stress proteins
-
批准号:24790077
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.83万
-
财政年份:2012
-
负责人:TANAKA Kenichiro
-
依托单位:
Study of accurate numerical methods and verified computation relating to stochastic differential equations
-
批准号:24760064
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.75万
-
财政年份:2012
-
负责人:TANAKA Kenichiro
-
依托单位:
Elucidation of reaction mechanism of site-specific chemical bond scission on self-assembled monolayers as a reaction platform
-
批准号:21350014
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$12.31万
-
财政年份:2009
-
负责人:TANAKA Kenichiro
-
依托单位:
Dynamics of Site-Specific Ion Desorption Reactions
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批准号:16205002
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$29.54万
-
财政年份:2004
-
负责人:TANAKA Kenichiro
-
依托单位:
Dynamical study of surface photochemistry by VUV radiation
-
批准号:03453024
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$0.64万
-
财政年份:1991
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负责人:TANAKA Kenichiro
-
依托单位:
Site-specific photochemistry following soft x-ray irradiation
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批准号:61470018
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$3.2万
-
财政年份:1986
-
负责人:TANAKA Kenichiro
-
依托单位:
海外基金