Diagnostic method of Helicobacter heilmannii infection based on genetic analysis

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Helicobacter heilmannii infection is possibly associated with gastric MALT lymphoma in mice model and human, and however, its diagnostic method has not been established yet. In this study, we succeed in the diagnosis of its infection with gastric mucosa by analyzing pathogenic genes of H. pylori and H. heilmannii. In the next step, we tried to establish the serodiagnosis using monoclonal antibody, but our antibody showed cross-reactivity. Therefore, we are going on analyzing the other virulent genes.