Diagnostic method of Helicobacter heilmannii infection based on genetic analysis

海尔曼氏幽门螺杆菌感染可能与小鼠和人胃MALT淋巴瘤有关，但其诊断方法尚未建立。在本研究中，我们通过对幽门螺杆菌和海尔曼氏杆菌致病基因的分析，成功地诊断出其对胃粘膜的感染。在下一步，我们试图用单抗建立血清学诊断，但我们的抗体显示出交叉反应。因此，我们正在继续分析其他毒力基因。

Helicobacter heilmannii infection is possibly associated with gastric MALT lymphoma in mice model and human, and however, its diagnostic method has not been established yet. In this study, we succeed in the diagnosis of its infection with gastric mucosa by analyzing pathogenic genes of H. pylori and H. heilmannii. In the next step, we tried to establish the serodiagnosis using monoclonal antibody, but our antibody showed cross-reactivity. Therefore, we are going on analyzing the other virulent genes.