Comprehensive analysis of the tyrosine metabolic enzymes included in the candidates of liver protection pathways
Comprehensive analysis of the tyrosine metabolic enzymes included in the candidates of liver protection pathways
批准号:
22790648
负责人:
HIYOSHI Mineyoshi
金额:
$1.75万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
点击翻译按钮获取中文摘要
英文摘要
In the damaged rat liver, soluble catechol-0-methyltransferase(COMT) increased as a phosphorylated form and decreased as a dephosphorylated form. This finding raised the possibility that the COMT protein is associated with liver function. To evaluate the association between COMT genotypes and liver function, we used data from the Japan Multi-Institutional Collaborative Cohort(J-MICC) Study. In this study, we revealed that a COMT polymorphism(rs4680 : Val158Met(G/ A)) affected liver function.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
Role of a tyrosine phosphorylation of SMG-9 in binding of SMG-9 to IQGAP and the NMD complex
SMG-9 酪氨酸磷酸化在 SMG-9 与 IQGAP 和 NMD 复合物结合中的作用
DOI:
10.1016/j.bbrc.2011.05.099
发表时间:
2011
期刊:
Biochemical and Biophysical Research Communications
影响因子:
3.1
作者:
[Takeda S., et al]
通讯作者:
et al
Dietary patterns and blood levels of PCDDs, PCDFs, and dioxin-like PCBs in 1656 Japanese individuals
DOI:
10.1016/j.chemosphere.2010.11.008
发表时间:
2011-01-01
期刊:
CHEMOSPHERE
影响因子:
8.8
作者:
[Arisawa, Kokichi, Uemura, Hirokazu, Nagai, Masaki]
通讯作者:
Nagai, Masaki
Gene variants in PPARD and PPARGC1A are associated with timing of natural menopause in the general Japanese population
PPARD 和 PPARGC1A 的基因变异与日本普通人群的自然绝经时间相关
DOI:
10.1016/j.maturitas.2011.12.021
发表时间:
2012
期刊:
Maturitas
影响因子:
4.9
作者:
[Uemura, H., Hiyoshi, M., Arisawa, K., Yamaguchi, M., Naito, M., Kawai, S., Hamajima, N., Matsuo, K., Taguchi, N., Takashima, N., Suzuki, S., Hirasada, K., Mikami, H., Ohnaka, K., Yoshikawa, A., Kubo M., and Tanaka, H]
通讯作者:
H
J-MICC Study Group. ADIPOQおよびADRB3遺伝子多型が自然閉経年齢に及ぼす影響についての検討
J-MICC 研究组。ADIPOQ 和 ADRB3 基因多态性对自然绝经年龄的影响的检查。
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[上村浩一, 日吉峰麗, 山口美輪, 中本真理子, 武田英雄, 嵩下賢, 高見栄喜, 北山淳, 澤近房和, 十田朋也, 有澤孝吉]
通讯作者:
有澤孝吉
DOI:
10.1016/j.chemosphere.2010.02.050
发表时间:
2010-04
期刊:
Chemosphere
影响因子:
8.8
作者:
[H. Uemura;K. Arisawa;M. Hiyoshi;Satoru Dakeshita;Atsushi Kitayama;Hidenobu Takami;Fusakazu Sawachika;Miwa Yamaguchi;Shuhei Sasai]
通讯作者:
H. Uemura;K. Arisawa;M. Hiyoshi;Satoru Dakeshita;Atsushi Kitayama;Hidenobu Takami;Fusakazu Sawachika;Miwa Yamaguchi;Shuhei Sasai
共 15 条