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Role of angiotensin II type 1 receptor in macrophage polarization and function

Role of angiotensin II type 1 receptor in macrophage polarization and function
血管紧张素 II 1 型受体在巨噬细胞极化和功能中的作用
批准号:
22790707
负责人:
SUZUKI Jun
金额:
$2.16万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011

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中文摘要
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英文摘要
Stimulation of the angiotensin II type 1 receptor induces macrophage polarization to inflammatory M1 state and activates macrophage phagocytic function. Angiotensin II type 1 receptor also plays an important role in oxidized LDL-induced macrophage trapping in the atherosclerotic lesions via enhancing CD36 expression and focal adhesion kinase activation. Our results suggest that stimulation of the angiotensin II type 1 receptor modulates macrophage polarity and functions, resulting in atherosclerotic plaque instability.
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会议论文
Deletion of the Angiotensin II Type 1a Receptor Prevents Athero sclerotic Plaque Rupture
血管紧张素 II 1a 型受体的缺失可预防动脉粥样硬化斑块破裂
DOI: --
发表时间: 2012
期刊: Arterioscle Thromb Vasc Biol
影响因子: --
作者: [Jun Aono, Jun Suzuki, et al]
通讯作者: et al
A Study on the Subversive Plots of Women's Desire in Sensation Fiction
  • 批准号:
    25770112
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
  • 资助金额:
    $1.25万
  • 财政年份:
    2013
  • 负责人:
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  • 批准号:
    24790278
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
  • 资助金额:
    $2.83万
  • 财政年份:
    2012
  • 负责人:
    SUZUKI Jun
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Economic studies of the roles of nonprofit organizations and the related policies: An application and extension of relational goods theory
  • 批准号:
    23530317
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.24万
  • 财政年份:
    2011
  • 负责人:
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A Reconsideration of the Complicit Relationship Between Nineteenth-Century British Imperialism and Fiction
  • 批准号:
    22720108
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
  • 资助金额:
    $1.0万
  • 财政年份:
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  • 负责人:
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