Risk prediction system of retinal disease based on retinal vascular changes.

视网膜静脉阻塞是日本失明的主要原因。在这项研究中，我们直接量化视网膜血管特征，旨在确定与视网膜血管疾病未来发展相关的局部眼部特征。我们发现与视网膜静脉阻塞风险增加相关的三个特征，即“孤立性视网膜病变”、“动静脉交叉角变窄”和“右眼和左眼动静脉比率不一致”。在这三个特征中，动静脉比的差异是一个潜在的适用于筛查方案的参数。

Retinal vein occlusion is a major cause of blindness in Japan. In this study, we directly quantified retinal vascular characteristics and aimed to determine local ocular characteristics associated with future development of the retinal vascular diseases. We identified three characteristics associated with increased risk of retinal vein occlusion, namely, “isolated retinopathy”, “narrowing of the arterio-venous crossing angle”, and a “discrepancy in the arterio-venous ratio between right eye and left eye”. Of the three characteristics, discrepancy in the arterio-venous ratio is a potential parameter applicable to screening program.