Study on development of a novel remedy using green tea catechin for Sjogren's syndrome
Study on development of a novel remedy using green tea catechin for Sjogren's syndrome
批准号:
22592082
负责人:
SAITO Keiichi
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
We administered epigallocatechin gallate (EGCG) to MRL-Faslprmice from age of 8 to 16weeks and examined suppressive effects of EGCG on autoimmune sialadenitis. Our results demonstrated that the rate of sialadenitis accompanied with tissue destruction decreased in EGCG-administered mice by 70% relative to EGCG-non-administered mice. The protective actions ofEGCG were ascribed to expression of heme oxygenase-1 and Bcl-2 which was enhanced by EGCG.
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DOI:
10.1016/j.ultrasmedbio.2010.07.015
发表时间:
2010-11-01
期刊:
ULTRASOUND IN MEDICINE AND BIOLOGY
影响因子:
2.9
作者:
[Horie, Sachiko, Watanabe, Yukiko, Kodama, Tetsuya]
通讯作者:
Kodama, Tetsuya
DOI:
10.1158/0008-5472.can-11-2389
发表时间:
2011-11-15
期刊:
CANCER RESEARCH
影响因子:
11.2
作者:
[Kodama, Tetsuya, Tomita, Noriko, Mori, Shiro]
通讯作者:
Mori, Shiro
Evaluation of antitumoreffects following tumor necrosis factor-alphagene delivery using nanobubbles and ultrasound
使用纳米气泡和超声评估肿瘤坏死因子-α基因递送后的抗肿瘤效果
DOI:
10.1111/j.1349-7006.2011.02084.x
发表时间:
2011
期刊:
Cancer Sci
影响因子:
5.7
作者:
[Satoh Y, Yajima E, Murakami T, Shiro Mori(他4名)]
通讯作者:
Shiro Mori(他4名)
Epigallocatechin gallate inhibits oxidative stress-induced DNA damage and apoptosis in MRL-Fas(lpr) mice with autoimmune sialadenitis via upregulation of heme oxygenase-1 and Bcl-2
表没食子儿茶素没食子酸酯通过上调血红素加氧酶-1和Bcl-2抑制自身免疫性唾液腺炎MRL-Fas(lpr)小鼠氧化应激诱导的DNA损伤和细胞凋亡
DOI:
10.3109/08916934.2013.850079
发表时间:
2014
期刊:
Autoimmunity
影响因子:
3.5
作者:
[Keiichi Saito, Shiro Mori, Fumiko Date, Masao Ono]
通讯作者:
Masao Ono
DOI:
10.1007/978-4-431-54070-0
发表时间:
2012
期刊:
影响因子:
--
作者:
[K. Sasaki;O. Suzuki;N. Takahashi;P. Stashenko;M. Cambridge]
通讯作者:
K. Sasaki;O. Suzuki;N. Takahashi;P. Stashenko;M. Cambridge
共 10 条
An investigation of cognitive strategies employed in intake interviews by expert practitioners in clinical psychology.
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批准号:22500243
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.41万
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财政年份:2010
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负责人:SAITO Keiichi
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依托单位:
ROLES OF SALIVARY GLAND CELLS AS ANTIGEN PRESENTING CELLS IN PATHOGENESIS OF SJOGRENS SYNDROME
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批准号:17592175
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.33万
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财政年份:2005
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负责人:SAITO Keiichi
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依托单位:
Development of visibility estimation model using colors and contrasts
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批准号:15500142
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.6万
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财政年份:2003
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负责人:SAITO Keiichi
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依托单位:
INVOLVEMENT OF APOPTOTIC PATHWAY IN PATHOGENESIS OF SJOGRENS SYNDROME
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批准号:14571935
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.43万
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财政年份:2002
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负责人:SAITO Keiichi
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依托单位:
POSSIBILITY OF CARCINOGENESIS IN DRUG-INDUCED GINGIVAL HYPERPLASIA
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批准号:07807188
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.34万
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财政年份:1995
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负责人:SAITO Keiichi
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依托单位:
海外基金