Reevaluation of α-tricalcium phosphate foam which is not suitable for bone substitute material

α-磷酸三钙泡沫不适用于骨替代材料的再评价

• 批准号: 22592184
• 负责人: UDOH Koh-ichi
• 金额: $ 3万
• 依托单位: Yamaguchi University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22592184/
• 关键词: α型リン酸三カルシウム; 骨補填材; 足場材; フォーム; 骨補填剤; リン酸カルシウム; リン酸三カルシウム; 3次元連通気孔

Fully interconnected -TCP foam was able to be fabricated using the polyurethane foam method, whereby polyurethane foam coated with -TCP slurry was sintered at 1,450 1,550°C and that no quenching was performed. The -TCP foam had extremely high porosity ranging between 90 and 95% and exhibited reasonable compressive strength ranging between 50 and 250 kPa. Based on these initial findings, it is highly recommended that in vivo evaluation be carried out to explore the possibility and suitability of -TCP foam as a bone substitute and/or scaffolding material for tissue engineering.

采用聚氨酯泡沫法能够制备完全互联的聚氯乙烯泡沫塑料，该方法是在1,450-1,550°C下烧结涂覆了聚四氟乙烯浆料的聚四氟乙烯泡沫，并且不进行淬火。-TCP泡沫具有非常高的孔隙率，范围在90%到95%之间，并且具有合理的压缩强度，范围在50到250kpa之间。基于这些初步发现，强烈建议进行体内评估，以探索-TCP泡沫作为组织工程骨替代和/或支架材料的可能性和适用性。

项目成果

The enhancement of tumor radioresponse by combined treatment with cepharanthine is accompanied by the inhibition of DNA damage repair and the induction of apoptosis in oral squamous cell carcinoma

• DOI: 10.3892/ijo.2012.1501
• 发表时间: 2012-08-01
• 期刊: INTERNATIONAL JOURNAL OF ONCOLOGY
• 影响因子: 5.2
• 作者: Harada, Toyoko;Harada, Koji;Ueyama, Yoshiya
• 通讯作者: Ueyama, Yoshiya

Effects of sintering temperature on physical and compositional properties of .ALPHA.-tricalcium phosphate foam

烧结温度对.ALPHA.-磷酸三钙泡沫物理和成分性能的影响

• DOI: 10.4012/dmj.2009-079
• 发表时间: 2010
• 期刊: Dental Materials Journal
• 影响因子: 2.5
• 作者: K.udoh;ほか4名
• 通讯作者: ほか4名

口腔扁平上皮癌における分子標的薬Bortezomib とTS-1 の併用効果についての基礎的研究

分子靶向药物硼替佐米与TS-1联合治疗口腔鳞癌的基础研究

• 发表时间: 2011
• 期刊: 頭頸部
• 作者: 原田豊子;原田耕志;上山吉哉
• 通讯作者: 上山吉哉

Comparison of apatite-coated titanium prepared by blast coating and flame spray methods-Evaluation using simulated body fluid and initial histological study

喷砂和火焰喷涂方法制备的磷灰石涂层钛的比较-使用模拟体液进行评估和初步组织学研究

• 发表时间: 2011
• 期刊: Dental Materials Journal
• 影响因子: 2.5
• 作者: Mano T;Ishikawa K;Harada K;Uchida H;Ueyama Y
• 通讯作者: Ueyama Y

Effects of sintering temperature on physical and compositional properties of a-tricalcium phosphate foam

烧结温度对α-磷酸三钙泡沫物理和成分性能的影响

• 发表时间: 2010
• 期刊: Dent Mater J
• 影响因子: 2.5
• 作者: Udoh K,Munar M.L;Maruta M;Matsuya S;Ishikawa K
• 通讯作者: Ishikawa K