The effects ofanesthetics onperipheral nerve regeneration

我们在体外将小鼠骨髓基质细胞（BMSCs）分化为雪旺细胞。我们认为骨髓间充质干细胞在向雪旺细胞分化的培养条件下需要抗坏血酸和谷氨酸。我们还研究了全麻和局麻对骨髓间充质干细胞来源的雪旺细胞的影响，结果表明，全麻、异丙酚和局麻、利多卡因对骨髓间充质干细胞来源的雪旺细胞有抑制作用。

We differentiated murine bone marrow stromal cells (BMSCs) into Schwann cells in vitro. We suggests that BMSCs needs ascorbic acids and glutamic acids in the culture condition of differentiation into Schwann cells. We also examined the effects of general anesthetics and a local anesthetic onSchwann cells derived from BMSCs, which results suggest that a general anesthetic, propofol and a local anesthetic, lidocaine had the inhibitory effects on Schwann cells derived from BMSCs.