How periodontitis can affect prostate cancer metastasis?

在目前的研究中，我们证明了局部炎症反应和全身炎症反应之间的相反关联。我们的发现表明，可能需要适当的感染性接触来维持我们的生命。综上所述，菌血症引发的严重败血症可能是与牙龈假单胞菌感染相关的死亡原因，但免疫系统将调节不必要的全身反应。这些全身性反应也可能影响转移性癌症。

In the present study, we demonstrated the opposite association between localized and systemic inflammatory responses. Our finding suggests that appropriate infectious exposure might be needed to maintain our life. Taken together, a severe sepsis-like condition elicited by bacteremia, is likely responsible for the mortality associated with P. gingivalisinfection, but immune system would regulate the unwanted systemic responses. These systemic responses may alsoimpact metastatic cancer.