Healthful regulation of body fat percentage by somatolactin

生长抑素对身体脂肪百分比的健康调节

• 批准号: 22651074
• 负责人: FUKAMACHI Shoji
• 金额: $ 2.2万
• 依托单位: Japan Women's University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22651074/
• 关键词: メダカ; ソマトラクチン; 脂肪率

It has been indicated that somatolactin(SLa) would function to regulate triglycerides in the muscles and liver. The purpose of this study is to verify the function and explore a possibility for its application to fisheries. Using the mutant and transgenic strains of the SLa gene which were bred under various breeding conditions, we found that the internal/external environments(age and foods) have more effects on percent hepatic triglycerides than the SLa expression.

生长抑素（somatolactin，SLa）具有调节肌肉和肝脏甘油三酯的功能。本研究的目的是验证其功能并探索其在渔业中应用的可能性。使用突变体和转基因菌株的SLa基因，这是在各种育种条件下繁殖，我们发现，内部/外部环境（年龄和食物）有更多的影响比SLa表达的肝甘油三酯百分比。