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Sensitive and selective biochemical sensing with nan-structured surface on an optical element

Sensitive and selective biochemical sensing with nan-structured surface on an optical element
光学元件上具有纳米结构表面的灵敏和选择性生化传感
批准号:
22656039
负责人:
MORONUKI Nobuyuki
金额:
$2.21万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011

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中文摘要
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英文摘要
High sensitive matter detection is possible by applying antigen-antibody reaction, one of the biochemical sensing methods. However, fluorescence microscope and/or other analysis equipment are required and the system tends to be complicated. This study aims to simplify such system by combining fluorescent intensity improvement by nano-/microstructuring produced with self-assembly of fine particles on an optical lens and its condensation effect. It was found that the fluorescent intensity was improved up to 6 times compared to a planer substrate without fine structure. However, the improvement is limited by the scattering effect of the fine structure.
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会议论文
光学素子表面に整列させた機能性微粒子による生化学分析の高感度化
利用光学元件表面排列的功能性微粒提高生化分析的灵敏度
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Etsuo Maeda, Takanori Matsuki, Ichiro Yamada, Jean-Jacques Delaunay, 欅徳人,諸貫信行,田中靖紘,西尾学,金子新, 西尾学,諸貫信行,田中靖紘,金子新]
通讯作者: 西尾学,諸貫信行,田中靖紘,金子新
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [N. Moronuki, M. Nishio, and A. Kaneko]
通讯作者: and A. Kaneko
High Sensitive Biosensing Using Microstructured Surface
使用微结构表面的高灵敏度生物传感
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Y.Tanaka, A.Kaneko, N.Moronuki]
通讯作者: N.Moronuki
表面の微細構造化によるイムノアッセイの高感度化
通过表面微结构提高免疫测定的灵敏度
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Etsuo Maeda, Takanori Matsuki, Ichiro Yamada, Jean-Jacques Delaunay, 欅徳人,諸貫信行,田中靖紘,西尾学,金子新]
通讯作者: 欅徳人,諸貫信行,田中靖紘,西尾学,金子新
13
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