Does gene duplication enhance the evolution of herbicide resistancein weeds?

以乙酰乳酸合成酶抑制型除草剂磺酰脲类除草剂、抗病单胞菌和黑麦草为材料，研究了杂草中基因复制与除草剂抗性进化的关系。这两种水稻杂草是异源四倍体。阴道假丝核菌和黑曲霉都有多个乙酰乳酸合成酶基因，至少两个乙酰乳酸合成酶基因的单核苷酸替换是赋予其对磺酰脲类除草剂抗性所必需的。

The relationship between gene duplication and evolution of herbicide resistance in weeds was investigated using sulfonylurea herbicide, one of acetolactate synthase inhibiting herbicides, resistant Monochoria vaginalis and M. korsakowii. These two paddy weeds are allotetraploid. Both M. vaginalis and M. korsakowii have multiple acetolactate synthase genes and single nucleotide substitution at least two acetolactate synthase genes was necessary to confer sulfonylurea herbicide resistance.