Analysis of evidence-practice gap using healthcare claims(receipts) database : with special reference to implementation of the recommendations in the clinical practice guidelines and adherence to the alert in package insert.

使用医疗保健索赔（收据）数据库分析证据与实践差距：特别参考临床实践指南中建议的实施以及对包装说明书中警报的遵守。

• 批准号: 22659102
• 负责人: NAKAYAMA Takeo
• 金额: $ 1.73万
• 依托单位: Kyoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22659102/
• 关键词: J医療の質

In recent years, the problem of underuse of useful clinical evidence is coming to be important-evidence-practice gap. The major concern about evidence-practice gap is insufficient implementation of evidence-based effective treatment, however, the perspective can be extended to measures to improve drug safety and prevention of drug related adverse events. At first, this study characterized the database of receipt(healthcare claims) and the usefulness for research purpose. Afterwards, two cases(implementation of recommendation of preventive drug use against steroid-induced osteoporosis, adherence to the alert indicated in revised package insert for ergot-derived anti-Parkinson drugs, of which risk of valvulopathy has been identified) were examined using this database. Through these analyses, the receipt database was proved to be useful to study evidence-practice gap.

近年来，有用的临床证据利用不足的问题日益成为重要的证据-实践差距。证据-实践差距的主要关注是循证有效治疗的实施不足，但视角可以扩展到提高药物安全性和预防药物相关不良事件的措施。首先，这项研究表征了收据数据库(医疗索赔)和研究目的的有用性。然后，使用该数据库检查两个案例(执行类固醇诱导性骨质疏松症预防用药建议，遵守修订的麦角衍生抗帕金森药物包装插页中指示的警示，其中已确定存在瓣膜病的风险)。通过这些分析，收据数据库被证明是研究证据-实践差距的有用工具。

项目成果

薬剤疫学とリスクコミュニケーション

药物流行病学和风险沟通

• 发表时间: 2011
• 作者: Koinuma N;Wilking N E;Jonsson B;Hogberg D;山岡吉生;中山健夫
• 通讯作者: 中山健夫

10 years history of CPGs(Clinical Practice Guidelines) development in Japan

日本CPG（临床实践指南）发展10年历程

• 发表时间: 2011
• 作者: Suzuki H;Nakayama T;Tsutani K
• 通讯作者: Tsutani K

保健医療情報分析活用研究会

健康与医疗信息分析利用研究组

Adherence in performing echocardiography to detect valvulopathy associated with the use of ergot-derived dopamine agonists in patients with Parkinson's disease.

坚持进行超声心动图检查，以检测帕金森病患者与使用麦角衍生的多巴胺激动剂相关的瓣膜病。

• 期刊: Internal Medicine
• 影响因子: 1.2
• 作者: Nakaoka S;Ishizaki T;Urushibara H;Sato T;Ikeda S;Noda M;Morikawa K;Nakayama T
• 通讯作者: Nakayama T

Development of a database of health insurance claims: standardization of disease classifications and anonymous record linkage.

• DOI: 10.2188/jea.je20090066
• 发表时间: 2010
• 期刊: Journal of epidemiology
• 影响因子: 4.7
• 作者: Kimura S;Sato T;Ikeda S;Noda M;Nakayama T
• 通讯作者: Nakayama T