THE ENERGY REQUIREMENTS IN INDIVIDUALS WITH MENTAL RETARDATION
智力障碍人士的能量需求
基本信息
- 批准号:07670427
- 负责人:
- 金额:$ 1.54万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (C)
- 财政年份:1995
- 资助国家:日本
- 起止时间:1995 至 1997
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
To characterize energy metabolism in individuals with mental retardation (MRs), We meaured energy cost at several physical activity levels (basal, supine, siffting, standing, and walking at 30,50 and 70 m/min), maximal oxygen consumption (Vo_2max), and body composition in 23 male MRs and the same number of volunteer male controls. Both groups were individually matched for age, body height, and body weight. Energy costs were measured by the Douglas bag technique. The recently developed sulfur hexafluoride (SF_6) dilution technique was employed for measuring body composition.In addition, 3-dimensional accelerometry was used for evaluating body movements, and plasma indices of macronutrients were also measured. Results : The energy cost of MRs, when sitting, standing, and walking at 30 and 50 m/min, was significantly higher than that of controls (p<0.05), while the basal and resting metabolic rates were similar in both groups. Vo_2max was significantly lower (P<0.05) in MRs than controls. Accelerometry demonstrated excessive movements in MRs, which may explain their higher energy cost of exercise. By contrast, no significant difference was observed in percent body fat and lean body mass. Concentrations of plasma total cholesterol, triacylglycerols and albumin were significantly lower in MRs compared with controls.Our findings suggest that MRs are burdened with energy metabolism less economical than non-MRs. A limited physical activity in their daily life may be the cause. These characteristics of MRs' energy metabolism should be considered for planning their proper dietary schdules and physical activity programs
为了解智力低下(MR)个体能量代谢的特点,我们测定了23例MR和相同数量的男性志愿者在不同体力活动水平(基础、仰卧、站立、30、50和70 m/min步行)下的能量消耗、最大耗氧量(Vo_2max)和身体成分。两组在年龄、身高和体重方面均单独匹配。能量消耗用道格拉斯袋法测量。采用新近发展起来的六氟化硫(SF_6)稀释法测定体成分,用三维加速度计评价体运动,并测定血浆中大量营养素指数。结果如下:当坐着、站立和以30和50 m/min行走时,MR的能量消耗显著高于对照组(p<0.05),而两组的基础代谢率和静息代谢率相似。最大摄氧量(Vo 2 max)在二尖瓣返流组显著低于对照组(P<0.05)。加速度计显示MR的过度运动,这可能解释了他们运动的更高能量消耗。相比之下,在体脂百分比和瘦体重方面没有观察到显著差异。血浆总胆固醇、三酰甘油和白蛋白的浓度在MR患者中显著低于对照组。我们的研究结果表明,MR患者的能量代谢负担比非MR患者低,日常生活中有限的体力活动可能是原因。因此,在制定合理的膳食计划和体育锻炼计划时,应考虑代谢综合征患者能量代谢的特点
项目成果
期刊论文数量(4)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Iwaoka H, Yokoyama T et al.: "Characteristics of energy metabolism in males with mental retardation" Journal of Nutritional Science and Vitamindogy. 44・1. 151-164 (1998)
Iwaoka H、Yokoyama T 等:“精神障碍男性的能量代谢特征”《营养科学与维生素学杂志》44・1(1998 年)。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
岩岡浩子・横山徹爾・中山健夫: "知的障害者と健常者との動作別エネルギー消費量の差異に関する検討" 日本公衆衛生雑誌〈特別付録〉. 43巻10号. 828- (1996)
Hiroko Iwaoka、Tetsuji Yokoyama、Takeo Nakayama:“智力障碍者与健康人之间运动能量消耗的差异研究”日本公共卫生杂志(特刊)第 43 卷,第 10 期。828-(1996 年)。 )
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
Iwaoka H, Yokoyama T et al.: "Characteristics of energy metabolism in males with mental retardation" Journal of Nutritional Science and Vitaminology. 44・1. 151-164 (1998)
Iwaoka H、Yokoyama T 等:“精神障碍男性的能量代谢特征”《营养科学与维生素学杂志》44・1(1998 年)。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
Iwaoka H,Yokoyama T,Masayasu S,Fuchi T,Nakayama T,Tanaka H.: "Characteristics of energy metabolism in males with mental retardation" Journal of Nutritional Science and Vitaminology. 44. 151-164 (1998)
Iwaoka H,Yokoyama T,Masayasu S,Fuchi T,Nakayama T,Tanaka H.:“精神发育迟滞男性的能量代谢特征”营养科学和维生素学杂志。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
NAKAYAMA Takeo其他文献
気道熱傷の病態と治療、そして今後の展望について
呼吸道烧伤的病理学、治疗及未来展望
- DOI:
- 发表时间:
2016 - 期刊:
- 影响因子:0
- 作者:
MANO Fumika;IKEDA Kaori;SATO Tosiya;NAKAYAMA Takeo;TANAKA Daisuke;JOO Erina;TAKAHASHI Yoshimitsu;KOSUGI Shinji;SEKINE Akihiro;TABARA Yasuharu;MATSUDA Fumihiko;INAGAKI Nobuya;Nagahama Study Group;田崎修 - 通讯作者:
田崎修
NAKAYAMA Takeo的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('NAKAYAMA Takeo', 18)}}的其他基金
Development of new electronic health record (EHR) systems that aim to apply for epidemiologic studies and patients support
开发新的电子健康记录(EHR)系统,旨在应用于流行病学研究和患者支持
- 批准号:
26670315 - 财政年份:2014
- 资助金额:
$ 1.54万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
Characteristics of people who are screened to be positive but do not consult a physician for clinical follow-up: epidemiologic and qualitative research
筛查结果呈阳性但未咨询医生进行临床随访的人群的特征:流行病学和定性研究
- 批准号:
24659320 - 财政年份:2012
- 资助金额:
$ 1.54万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
Analysis of evidence-practice gap using healthcare claims(receipts) database : with special reference to implementation of the recommendations in the clinical practice guidelines and adherence to the alert in package insert.
使用医疗保健索赔(收据)数据库分析证据与实践差距:特别参考临床实践指南中建议的实施以及对包装说明书中警报的遵守。
- 批准号:
22659102 - 财政年份:2010
- 资助金额:
$ 1.54万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
Research on the development of infrastructure for creation, communication and utilization of healthcare information
医疗信息创建、传播和利用的基础设施建设研究
- 批准号:
18209018 - 财政年份:2006
- 资助金额:
$ 1.54万 - 项目类别:
Grant-in-Aid for Scientific Research (A)
A Multi-Center Prospective Registration and Cohort Study on Prognosis and Predictors of Acute Myocardial Infarction in Japan.
日本急性心肌梗死的预后和预测因素的多中心前瞻性登记和队列研究。
- 批准号:
14207102 - 财政年份:2002
- 资助金额:
$ 1.54万 - 项目类别:
Grant-in-Aid for Scientific Research (A)
相似海外基金
A Novel Role of Fragile-X Mental Retardation Protein in Mitochondrial Calcium Homeostasis
Fragile-X 智力迟钝蛋白在线粒体钙稳态中的新作用
- 批准号:
10452354 - 财政年份:2022
- 资助金额:
$ 1.54万 - 项目类别:
A Novel Role of Fragile-X Mental Retardation Protein in Mitochondrial Calcium Homeostasis
Fragile-X 智力迟钝蛋白在线粒体钙稳态中的新作用
- 批准号:
10612482 - 财政年份:2022
- 资助金额:
$ 1.54万 - 项目类别:
Role of Fragile X Mental Retardation Protein on Gene Expression in Auditory Brainstem Development
脆性X智力低下蛋白对听觉脑干发育中基因表达的作用
- 批准号:
10350694 - 财政年份:2021
- 资助金额:
$ 1.54万 - 项目类别:
Role of Fragile X Mental Retardation Protein on Gene Expression in Auditory Brainstem Development
脆性X智力低下蛋白对听觉脑干发育中基因表达的作用
- 批准号:
10934302 - 财政年份:2021
- 资助金额:
$ 1.54万 - 项目类别:
Fragile X Mental Retardation 1 gene: a master switch of ovarian communication and oocyte quality.
脆性 X 智力低下 1 基因:卵巢通讯和卵母细胞质量的主开关。
- 批准号:
RGPIN-2017-04775 - 财政年份:2021
- 资助金额:
$ 1.54万 - 项目类别:
Discovery Grants Program - Individual
Role of Fragile X Mental Retardation Protein on Gene Expression in Auditory Brainstem Development
脆性X智力低下蛋白对听觉脑干发育中基因表达的作用
- 批准号:
10593043 - 财政年份:2021
- 资助金额:
$ 1.54万 - 项目类别:
Role of Fragile X Mental Retardation Protein on Gene Expression in Auditory Brainstem Development
脆性X智力低下蛋白对听觉脑干发育中基因表达的作用
- 批准号:
10190073 - 财政年份:2021
- 资助金额:
$ 1.54万 - 项目类别:
Fragile X Mental Retardation 1 gene: a master switch of ovarian communication and oocyte quality.
脆性 X 智力低下 1 基因:卵巢通讯和卵母细胞质量的主开关。
- 批准号:
RGPIN-2017-04775 - 财政年份:2020
- 资助金额:
$ 1.54万 - 项目类别:
Discovery Grants Program - Individual
an new approach the pathogenesis of mental retardation from the abnormality of microglia by postnatal mental stress.
产后精神应激导致小胶质细胞异常,为智力低下的发病机制提供了新途径。
- 批准号:
19K08353 - 财政年份:2019
- 资助金额:
$ 1.54万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Fragile X Mental Retardation 1 gene: a master switch of ovarian communication and oocyte quality.
脆性 X 智力低下 1 基因:卵巢通讯和卵母细胞质量的主开关。
- 批准号:
RGPIN-2017-04775 - 财政年份:2019
- 资助金额:
$ 1.54万 - 项目类别:
Discovery Grants Program - Individual














{{item.name}}会员




