Role of amine-carbonyl reaction as a novel mechanism for renal disease
Role of amine-carbonyl reaction as a novel mechanism for renal disease
批准号:
22659164
负责人:
ITO Sadayoshi
金额:
$2.07万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
The study was designed to evaluate whether reaction between amine and carbonyl compound is a novel mechanism for renal injury. Renal injury was observed by co-administration of MGO and melamine or oxonic acid. This reaction was also inhibited by pyridoxamine treatment. These results indicate that amine-carbonyl reaction could be a novel therapeutic mechanism which could be targeted for renal injuries.
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心腎連関と尿酸
心肾联系和尿酸
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Shibata S, Fujita T, 伊藤貞嘉]
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伊藤貞嘉
腎血流、今月の特集・理解のためのチェックリスト
肾血流量,本月专题/了解清单
DOI:
--
发表时间:
2011
期刊:
月刊循環器Circulation
影响因子:
--
作者:
[Kanematsu T, Yano S, et al., 伊藤貞嘉]
通讯作者:
伊藤貞嘉
高血圧・代謝疾患領域での臨床応用
高血压及代谢性疾病领域的临床应用
DOI:
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发表时间:
2011
期刊:
影响因子:
--
作者:
[Kawarazaki H, Fujita T, et al., 山田忠明, 森建文]
通讯作者:
森建文
若年肥満者における尿中カルボニル物質による血圧上昇の予測
年轻肥胖者尿液中羰基物质导致血压升高的预测
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Garry L. Corthals, Catherine E. Costello, Eric W. Deutsch, Bruno Domon, William Hancock, Fuchu He, Denis Hochstrasser, Gyorgy Marko-Varga, Ghasem Hosseini Salekdeh, Salvatore Sechi, Michael Snyder, Sudhir Srivastava, Mathias Uhlen, Cathy H. Hu, Tadashi Y, 佐藤恵美子]
通讯作者:
佐藤恵美子
糖尿病慢性合併症(大血管症);内分泌・糖尿病内科学
糖尿病慢性并发症(大血管病);内分泌/糖尿病医学;
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[小川晋, 他]
通讯作者:
他
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