Intraoperative autotransfusion Inactivation of bacillus and tumor cell in the collection blood from operative field by UVC irradiation

术中自体输血 UVC 照射灭活术野采集血液中的杆菌和肿瘤细胞

• 批准号: 22659281
• 负责人: KOJIMA Osamu
• 金额: $ 1.94万
• 依托单位: Shiga University of Medical Science
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22659281/
• 关键词: 術中回収式自己血輸血; 細菌; 腫瘍細胞; 紫外線; 腫瘍; 不活化; 紫外線LED; 回収式自己血輸血

The bacillus and the tumor cell will mix with the blood that bled while operating on cancer surgery. It is not possible to use it to transfuse. The inactivation of mixing bacillus and tumor cell was possible by the irradiation using UVC-LED. However, it was disturbed with the blood corpuscle and the exposure to UVC irradiation in blood was not enough. It was not possible to do during the study period though an appropriate thickness of the irradiation layer and the search of the stir operation etc. were also necessary. The possibility of autotransfusion was found in the cancer operation.

细菌和肿瘤细胞会与癌症手术时流血的血液混合。不可能用它来输血。UVC-LED照射可灭活混合芽孢杆菌和肿瘤细胞。但它受到血球的干扰，暴露在血液中的紫外线照射不足。在研究期间不可能做到这一点，尽管还需要适当的照射层厚度和搅拌操作的搜索等。在癌症手术中发现了自体输血的可能性。