Energy metabolism and muscle pathology in denervated swallowing muscles

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Swallowing mechanism are very complicated and muscle pathology of the swallowing muscles has yet to be clarified. Histochemical characteristics of the human masticatory muscles and swallowing muscles were investigated in this study. Experimental studies of soft diet and sympathectomy using young rabbits were also performed. Human masseter muscle and swallowing muscle showed unique histochemical characterstics reflecting highly differentiated masticatory and swallowing function. The soft diet experiment showed transformation of the muscle fiber types. Symathectomy experiment suggested that sympathetic nerve modulates differentiatin and metabolism of the muscle fibers.