COMPREHENSIVE HOME CARE OF CHILDREN WITH FOP (Fibrodysplasia Ossificans Progressiva)

FOP（进行性骨化性纤维发育不良）儿童的综合家庭护理

• 批准号: 22659409
• 负责人: KUWATA Hiromi
• 金额: $ 2.02万
• 依托单位: Shiga University of Medical Science
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22659409/
• 关键词: 小児看護学; 創薬; FOP; 質的研究; SBDD; 実態調査

FOP is a rare disease in which muscles in the body gradually replaced with bones. The aim of this study isto investigate the actual situation of home care for FOP patients and to consider the possible nursing home care for FOP patients. FOP patients kept moving in mind possible when they could move in in their childhood. FOP children are now dependent on their families, they hope to live their own life in future. Most of mothers experienced to promote their children’s independences. Using logical drug design method, we searched compounds, especially nutrienrs which can interact with ACVR1 mutation region, around H206, and found several compounds including masoprocol and enoximone as possible candidates.

FOP是一种罕见的疾病，身体中的肌肉逐渐被骨骼取代。本研究的目的是调查FOP患者家庭护理的实际情况，并考虑为FOP患者提供家庭护理的可能性。FOP患者在童年可以搬进来的时候，不断地在脑海中移动。FOP的孩子现在依赖于他们的家庭，他们希望未来能过上自己的生活。大多数母亲都经历过促进孩子独立的经历。采用合理的药物设计方法，在H206附近寻找与ACVR1突变区域相互作用的化合物，发现异丙醇和依诺酮等化合物为可能的候选化合物。

项目成果

Home care of children with FOP

FOP 儿童的家庭护理

• 发表时间: 2012
• 作者: H. Kuwata;H. Soga;M. Shirasaka;K. Kuwata
• 通讯作者: K. Kuwata

滋賀医科大学医学部臨床看護学講座小児看護学 研究成果【FOP患児の包括的生活支援】

滋贺医科大学临床护理学部儿科护理研究成果【FOP患儿的综合生命支持】

Fibrodysplasia ossificans progressiva研究の最近の知見と看護的課題

进行性骨化性纤维发育不良研究的最新发现和护理挑战

• 发表时间: 2010
• 期刊: 滋賀医科大学看護学ジャーナル
• 作者: 桑田弘美;白坂真紀;桑田一夫
• 通讯作者: 桑田一夫

Families' experiences of the heterotopic ossification occured in children with FOP

FOP患儿异位骨化的家庭经历

• 发表时间: 2013
• 作者: Hiromi Kuwata;Hiroyoshi Soga;Maki Shirasaka;Hisayo Okayama;Aki Yamaji;Yuko Tomari
• 通讯作者: Yuko Tomari

The school life of Child with Fibrodysplasia Ossificans Progressiva (FOP)

进行性骨化性纤维发育不良 (FOP) 儿童的学校生活

• 发表时间: 2013
• 作者: Hiromi Kuwata;Maki Shirasaka;Aki Yamaji;Hiroyoshi Soga;Yuko Tomari;Kazuo Kuwata
• 通讯作者: Kazuo Kuwata