COMPREHENSIVE HOME CARE OF CHILDREN WITH FOP (Fibrodysplasia Ossificans Progressiva)

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FOP is a rare disease in which muscles in the body gradually replaced with bones. The aim of this study isto investigate the actual situation of home care for FOP patients and to consider the possible nursing home care for FOP patients. FOP patients kept moving in mind possible when they could move in in their childhood. FOP children are now dependent on their families, they hope to live their own life in future. Most of mothers experienced to promote their children’s independences. Using logical drug design method, we searched compounds, especially nutrienrs which can interact with ACVR1 mutation region, around H206, and found several compounds including masoprocol and enoximone as possible candidates.