Analysis on Inhibitory circuit control of critical period-Comparative study in mice and birds.

小鼠眼优势可塑性关键期的时间受皮层抑制回路发育的调控。在这项研究中，我们测试了这一原则是否适用于鸟类鸣叫学习的关键时期。发育中的雄性斑胸草雀大脑早期GABA的增强通过提前关闭感觉学习期而干扰了后期的鸣叫学习。提出了保守的临界期机制、抑制回路控制的关键期机制。

The timing of critical period of ocular dominance plasticity in mice are regulated with cortical inhibitory circuit development. In this study we have tested whether this principle can be applied to the critical period in bird song learning. Early GABA enhancement in the developmental birds brain disrupted later song learning in male zebra finches by closing sensory learning period earlier. Here we suggested conserved critical period mechanism, inhibitory circuit control of critical period.