Association between subjective happiness and physical functions from perspectives of disease prevention and health promotion

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The purposes of this study were to clarify the association between subjective happiness and physical functions, and to develop the effective strategy of health promotion. The present study indicated that sense of happiness was generated by function of the medial prefrontal cortex (mPFC), and has a role in suppressing the peripheral circulating pro-inflammatory cytokine levels. In addition, the present study indicated that the endocannabinoid system might be involved in the interaction between happiness and suppression of the cytokine secretion. The present findings could be applied to various scientific fields such as not only psychological but also clinical and pedagogical areas.