Evaluation of the effect of co-existing dissolved organic matters on the bioavailability of hydrophobic organic compounds

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The effect of co-existing dissolved organic matters on the bioavailability of hydrophobic organic compounds was evaluated using artificial cell membrane as surrogate of aquatic organisms in order to figure out toxicity reduction with dissolved organic matters. The bioavailability of pyrene, 1-hydoxypyrene, 1-aminopyrene and fluoxetine were decreased with their sorption to dissolved organic matters. The largest reduction was 1.1% in Arakawa river and 5.2% in sewage treatment plant effluent, respectively. The sorption coefficients of pyrene to them were comparable to colored river in the United States.