Experiment research on the therapeutic impact of low-magnitude vibrations on eraly-stage bone healing
Experiment research on the therapeutic impact of low-magnitude vibrations on eraly-stage bone healing
批准号:
23300165
负责人:
MATSUMOTO Takeshi
金额:
$11.15万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011-04-01 至 2014-03-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Promotion of bone healing is favorable for preventing the elderly from falling into osteoporosis, a bedridden state, or situation necessitating nursing care. This study was undertaken to evaluate the effect of low-magnitude whole-body vibration (WBV) on early-stage bone healing, mainly focusing on angiogenesis. Mice subjected to a drill-hole surgery on a tibial diaphysis were exposed to 0.3g WBV at 30 Hz for 20 min/day over a 12-day period. Following vascular casting, the defect site was CT-scanned by synchrotron light. Structural analysis suggests the WBV-induced promotion of the defect repair with reduced angiogenesis. In addition, the second harmonic generation microscopy showed that WBV had no effect on collagen synthesis. Furthermore, the enhancement of angiogenesis under WBV did not increase the promotion effect of WBV on bone healing.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
放射光CTによる骨の形態・生理解析
使用同步辐射 CT 进行骨形态和生理分析
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Ugaki S, Takatani S, et al., Hiroshi Masuya, 金山翔一郎, 松本健志]
通讯作者:
松本健志
サブトラクション放射光CTによる骨欠損修復早期の骨再生及び血管新生定量イメージング
减影同步辐射CT对早期骨缺损修复过程中骨再生和血管生成的定量成像
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[後藤大智, 松本健志, 内藤尚, 田中正夫]
通讯作者:
田中正夫
Quantitative Bone CT Using Synchrotron Source
使用同步加速器源的定量骨 CT
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[桝屋啓志, 田中信彦, 鈴木智広, 若菜茂晴, T. Matsumoto]
通讯作者:
T. Matsumoto
In vivo CT quantification of trabecular bone dynamics in mice after sciatic neurectomy using monochromatic synchrotron radiation
使用单色同步辐射对坐骨神经切除术后小鼠骨小梁动力学进行体内 CT 量化
DOI:
--
发表时间:
2011
期刊:
Calcif.Tissue Int.
影响因子:
--
作者:
[Takeshi Matsumoto, et al.]
通讯作者:
et al.
DOI:
10.1038/labinvest.2013.87
发表时间:
2013-09-01
期刊:
LABORATORY INVESTIGATION
影响因子:
5
作者:
[Matsumoto, Takeshi, Goto, Daichi, Sato, Syota]
通讯作者:
Sato, Syota
共 15 条
4D imaging of arterial-wall fiber structure under pulsatile conditions by using synchrotron radiation phase-contrast CT
-
批准号:20K21899
-
项目类别:Grant-in-Aid for Challenging Research (Exploratory)
-
资助金额:$4.08万
-
财政年份:2020
-
负责人:MATSUMOTO Takeshi
-
依托单位:
4D imaging of bio-soft material deformation based on phase-contrast CT using synchrotron light
-
批准号:18K19926
-
项目类别:Grant-in-Aid for Challenging Research (Exploratory)
-
资助金额:$3.91万
-
财政年份:2018
-
负责人:MATSUMOTO Takeshi
-
依托单位:
Clarify the mechanism and dynamics characteristics of hung-up tree that is one of the causes for fetal accident
-
批准号:23658123
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.16万
-
财政年份:2011
-
负责人:MATSUMOTO Takeshi
-
依托单位:
Equivalence Checking for System-Level Designs Having Different Input-Output Timings
-
批准号:23700051
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.33万
-
财政年份:2011
-
负责人:MATSUMOTO Takeshi
-
依托单位:
Numerical study of elastic turbulence complementary to laboratory experiments
-
批准号:23740296
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$0.92万
-
财政年份:2011
-
负责人:MATSUMOTO Takeshi
-
依托单位:
Role of the Ryukyu Arc towards the Taiwan orogeny
-
批准号:21540439
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.75万
-
财政年份:2009
-
负责人:MATSUMOTO Takeshi
-
依托单位:
Spatio-temporal scaling law of unsteady turbulence : Rayleigh-Taylor turbulence
-
批准号:21740290
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$1.75万
-
财政年份:2009
-
负责人:MATSUMOTO Takeshi
-
依托单位:
Inhibitory effect of vitamin K2 on vascular calcification and osteoporosis : experimental approach to understanding the bone-vascular axis
-
批准号:21650112
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.21万
-
财政年份:2009
-
负责人:MATSUMOTO Takeshi
-
依托单位:
Experimental research on the development of a new therapy for bone injury via sympathetic nerve system
-
批准号:20300158
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.4万
-
财政年份:2008
-
负责人:MATSUMOTO Takeshi
-
依托单位:
Analysis of attractions of horntails wasps to volatiles from the hosts, relating the symbiotic fungus.
-
批准号:19780127
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$1.43万
-
财政年份:2007
-
负责人:MATSUMOTO Takeshi
-
依托单位:
Study on the active across-arc submarine faults and its relation-ship to large-scale tsunamis in the southwest Ryukyu arc
-
批准号:18540425
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.73万
-
财政年份:2006
-
负责人:MATSUMOTO Takeshi
-
依托单位:
Study on the angiogenesis-mediated promotion of bone fracture healing using repeated stimuli induced by microbubble destruction
-
批准号:17300152
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.72万
-
财政年份:2005
-
负责人:MATSUMOTO Takeshi
-
依托单位:
Evaluation of Coronary Vasoregulation Through Controlling Regional Myocardial Flow
-
批准号:07558134
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$2.37万
-
财政年份:1995
-
负责人:MATSUMOTO Takeshi
-
依托单位:
Non-basic D2 Receptor Binding Substances from Platns
-
批准号:01470029
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$3.14万
-
财政年份:1989
-
负责人:MATSUMOTO Takeshi
-
依托单位:
Chemical Structure of New Marine Diterpenes and Control of Their Biosynthesis
-
批准号:58430008
-
项目类别:Grant-in-Aid for General Scientific Research (A)
-
资助金额:$20.67万
-
财政年份:1983
-
负责人:MATSUMOTO Takeshi
-
依托单位:
国内基金
海外基金
登录
查看更多内容
基于HIF-1α乳酸化修饰探讨桃红四物汤调控BMSCs-H型血管新生轴促进骨折愈合的分子机制研究
-
批准号:2026JJ80362
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:周新
-
依托单位:
基于多组学揭示乳酸微环境中SPP1+肺癌细胞和SELE+内皮细胞促进血管新生的机制研究
-
批准号:2026JJ81608
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:陈双华
-
依托单位:
化痰通络汤调控PIEZO1/ACSL4/VEGF轴阻断线粒体机械转导增强内皮细胞铁死亡抗性促缺血性中风后血管新生的机制研究
-
批准号:2026JJ81884
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:朱新华
-
依托单位:
手术应激诱导ESM1分泌通过活化内皮细胞HMMR/FAK/SRC/NFκB信号轴促进卵巢癌血管新生的机制研究
-
批准号:2026JJ82422
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:夏丹
-
依托单位:
LECT2通过CBP/FOXO1轴调控内皮细胞周期参与心肌梗死后血管新生的机制研究
-
批准号:2026JJ60628
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:邹普
-
依托单位:
高糖诱导成纤维细胞外泌体GTF2H2介导血管新生抑制致糖尿病创面愈合障碍的机制研究
-
批准号:2026JJ82559
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:陈建民
-
依托单位:
活血荣络方诱导周细胞-内皮细胞间线粒体转移促脑梗死后血管新生的机制研究
-
批准号:2026JJ81885
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:刘利娟
-
依托单位:
PKCδ/EGR1/PHGDH 轴调控丝氨酸代谢促进内皮细胞衰老在糖尿病创面血管新生障碍中的机制研究
-
批准号:JCZRQNB202600620
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:
-
依托单位:
COL1A1-PI3K-AKT信号轴介导小胶质细胞神经炎症反应影响糖尿病视网膜病理性血管新生的机制研究
-
批准号:2026JJ81811
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:曹慧
-
依托单位:
去泛素化酶USP13通过调控SOCS1表达抑制小胶质细胞M1极化促进脑血管新生改善脑缺血再灌注损伤
-
批准号:2026JJ81103
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:王京微
-
依托单位: