Developement of a new stentless mitral valve for clinical application

1)动物实验：采用超声心动图评价无支架二尖瓣急性期血流动力学功能。无明显二尖瓣返流，舒张期平均二尖瓣压梯度低，表明无支架二尖瓣血流动力学性能良好。2)临床试验：9例患者使用无支架二尖瓣进行二尖瓣手术。所有患者进展顺利，无明显二尖瓣返流。平均二尖瓣压梯度较低；然而，随着时间的推移，它有增加的趋势。我们将继续密切关注这些患者。3)广告宣传：我们每年组织一次无支架二尖瓣年会，报告我们的早期和晚期手术结果，并讨论有关无支架二尖瓣的问题。建立了无支架瓣膜置换术患者登记系统。

1) Animal Experiment: We evaluated hemodynamic function of the stentless mitral valve with echocardiography in an acute phase using 8 pigs. No significant mitral regurgitation was found, and the mean mitral pressure gradient during diastole was low, which indicated excellent hemodynamic performance of the stentless mitral valve. 2) Clinical Trial: Nine patients underwent mitral surgery using the stentless mitral valve. All patients went well, and showed no significant mitral regurgitation. The mean mitral pressure gradient was reasonably low; however, it has a tendency towards increasing as time elapses. We continue to follow those patients carefully. 3) Advertisement and Propagation: We organize an annual meeting for stentless mitral valve to report our early and late surgical results and to discuss issues surrounding the stentless mitral valve. The registration system of patients undergoing the stentless valve was established.