Anti-aging trial through oxidative stress control in oral region

通过口腔区域氧化应激控制进行抗衰老试验

• 批准号: 23390480
• 负责人: MORITA Manabu
• 金额: $ 7.82万
• 依托单位: Okayama University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23390480/
• 关键词: 酸化ストレス; 栄養; 歯周病; 水素水; 歯周治療; アタアッチメントロス

The present clinical study aimed to clarify the interrelationship between periodontal health and dietary/hydrogen-rich water intake based on the systemic oxidative stress control. In the subjects with higher oxidative stress at baseline, relationship between periodontal disease progression and oxidative stress was apparent, whereas not with lower oxidative stress. The intake of 3 cups of coffee/day or more or intake of hydrogen-rich water showed inhibitory effect on periodontal disease.

本临床研究旨在从全身性氧化应激控制的角度阐明牙周健康与膳食/富氢水摄入量之间的相互关系。在基线氧化应激水平较高的受试者中，牙周疾病进展与氧化应激之间的关系是明显的，而与较低的氧化应激无关。每天摄入3杯或以上咖啡或摄入富氢水对牙周病有抑制作用。

项目成果

Longitudinal relationship between plasma reactive oxygen metabolites and periodontal condition in the maintenance phase of periodontal treatment

牙周治疗维持阶段血浆活性氧代谢物与牙周状况的纵向关系

• 发表时间: 2014
• 期刊: Disease Marker
• 作者: Machida T;Tomofuji T;Ekuni D;Yamane M;Yoneda T;Kawabata Y;Kataoka K. TamakiN;Morita M
• 通讯作者: Morita M

Relationship between plasma reactive oxygen species and progression of periodontitis

血浆活性氧与牙周炎进展的关系

• 发表时间: 2012
• 作者: Tamaki N;et al.
• 通讯作者: et al.