A novel intervention of phase II cardiac rehabilitation for patients with multiple complications to advance their social reintegration

针对多种并发症患者的 II 期心脏康复新干预措施，以促进他们重新融入社会

• 批准号: 23500612
• 负责人: MASUDA TAKASHI
• 金额: $ 3.24万
• 依托单位: Kitasato University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23500612/
• 关键词: 心臓; リハビリテーション; 自律神経活動; 多疾患有病者; 運動療法; 心臓リハビリテーション; 高齢者; 身体機能; 下肢筋力; 社会福祉サービス; 身体活動

Increased insulin resistance is closely correlated with exercise capacity in patients with hypertension (HT) and/or dyslipidemia (DL), because it is known to impair the energy metabolism in skeletal muscles. The aim of this study was to investigate the influence of insulin resistance on exercise capacity in patients with HT and/or DL.Homeostasis model assessment ratio (HOMA-R) was assessed and oxygen uptake (VO2) at anaerobic threshold (VO2 AT) and peak VO2 were measured by cardiopulmonary exercise testing. The exercise capacity was assessed using ratios of measured VO2 to predicted VO2 AT and predicted peak VO2 (%VO2 AT and %peak VO2, respectively).The %VO2 AT and %peak VO2 were significantly lower in the high HOMA-R group than in the low HOMA-R group (P<0.05, respectively), and negatively correlated with HOMA-R (r=0.339, P<0.05 and r=0.522, P<0.05, respectively). The present study showed that increased insulin resistance decreased exercise capacity in patients with HT and/or DL.

胰岛素抵抗增加与高血压（HT）和/或血脂异常（DL）患者的运动能力密切相关，因为已知它会损害骨骼肌的能量代谢。本研究的目的是探讨胰岛素抵抗对 HT 和/或 DL 患者运动能力的影响。通过心肺运动试验评估稳态模型评估比（HOMA-R）并测量无氧阈值（VO2 AT）的摄氧量（VO2）和峰值 VO2。使用测量VO2与预测VO2 AT和预测峰值VO2的比率（分别为％VO2 AT和％峰值VO2）来评估运动能力。高HOMA-R组的％VO2 AT和％峰值VO2显着低于低HOMA-R组（分别P<0.05），并且与HOMA-R呈负相关（r=0.339，P<0.05和r=0.522，P<0.05， 分别）。本研究表明，胰岛素抵抗增加会降低 HT 和/或 DL 患者的运动能力。

项目成果

Efects of electrical muscle stimulation in a left ventricular assist device patient

肌肉电刺激对左心室辅助装置患者的影响

• 发表时间: 2012
• 期刊: International Journal of Cardiology
• 影响因子: 3.5
• 作者: Kentaro Kamiya;Alessandro Mezzani;Takashi Masuda;Atsuhiko Matsunaga;Pantaleo Giannuzzi
• 通讯作者: Pantaleo Giannuzzi

Preventive effects of phase II cardiac rehabilitation against the rehospitalization in middle-aged patients with chronic heart failure

II期心脏康复对中年慢性心力衰竭患者再住院的预防作用

• 发表时间: 2013
• 作者: Takashi Masuda;Minoru Tabata;Kentaro Kamiya;Shuhei Yamamoto;Minako Yamaoka-Tojo;Tohru Izumi
• 通讯作者: Tohru Izumi

Stretching Exercises Attenuate Oxidative Stress and Vascular Endothelial Function in Heart Failure Patients with Implantable Cardioverter Defibrillator or Cardiac Resynchronization Therapy-defibrillator

伸展运动可减轻植入式心脏复律除颤器或心脏再同步治疗除颤器心力衰竭患者的氧化应激和血管内皮功能

• 发表时间: 2013
• 作者: Michitaka Kato;Takashi Masuda;Michio Ogano;Yuji Mori;Shota Kawase;Toshiyuki Ikedo;Ryosuke Shimizu;Kentaro Kamiya;Daisuke Kamemawa;Ayako Akiyama;Yumi Kamada;Shusuke Ota;Jun Tanabe;Takuya Umemoto
• 通讯作者: Takuya Umemoto

Neuromuscular electrical stimulation improves vascular endothelial function and peripheral circulation in patients with acute myocardial infarction

神经肌肉电刺激改善急性心肌梗死患者血管内皮功能和外周循环

• 发表时间: 2013
• 作者: S.Tanaka;K.Kamiya，K.Hotta，R.Shimizu，D.Kamekawa，A.Akiyama，Y.Kamada，N.Hamazaki，C.Noda，T.Masuda
• 通讯作者: K.Kamiya，K.Hotta，R.Shimizu，D.Kamekawa，A.Akiyama，Y.Kamada，N.Hamazaki，C.Noda，T.Masuda

Beneficial Effects of L- and N-type Calcium Channel Blocker on Glucose and Lipid Metabolism and Renal Function in Patients with Hypertension and Type II Diabetes Mellitus

• DOI: 10.1111/j.1755-5922.2009.00126.x
• 发表时间: 2011-01-01
• 期刊: CARDIOVASCULAR THERAPEUTICS
• 影响因子: 3.1
• 作者: Masuda, Takashi;Ogura, Misao N.;Izumi, Tohru
• 通讯作者: Izumi, Tohru