Role of dietary fiber in the body-Prevention from the lifestyle related disease-

饲喂含10%、5%和2%纤维素膳食纤维的40周龄雄性大鼠1周后，肝脏脂质合成系统基因表达受到抑制。虽然，在肝脏脂质水平方面，总胆固醇水平被认为通过增加纤维素的摄入量而显著增加。此外，由于膳食纤维摄入量的变化，肠道菌群也发生了显著变化。对纤维素摄入量引起胃肠道基因表达变化的观察报告表明，未被人体吸收的纤维素具有间接控制体内基因表达的功能。

In 40-week-old male wister rats reared for one week with food containing 10%, 5%, and 2% cellulose as dietary fiber, suppression of lipid synthesis system was seen in the gene expression of the liver. Although , in regard to lipid levels in liver, the total cholesterol level was seen to significantly increase by increasing the intake of cellulose. Also, a significant variation in the intestinal flora due to the variation of dietary fiber intake was detected. The observation of the change in gastrointestinal gene expression due to the amount of cellulose intake is the report which shows that cellulose that is not absorbed into the body has a function to indirectly control the gene expression in the body.