Brain mechanisms of heat stress-induced feeding suppression in neonatal chicks.

热应激引起的新生雏鸡摄食抑制的脑机制。

• 批准号: 23580404
• 负责人: KAWAKAMI Shin-ichi
• 金额: $ 3.49万
• 依托单位: Hiroshima University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23580404/
• 关键词: ニワトリ; 摂食行動; 暑熱; 神経伝達物質; 視床下部; 副腎皮質刺激ホルモン放出ホルモン; アルギニンバゾトシン; c-Fos

Exposure to high environmental temperature is known to negatively affect animal growth. One of the factors has been that heat stress strongly suppresses feeding behavior of animals, the mechanisms remain unknown. Therefore, the aim of the present study was to clarify the brain mechanisms regulating heat stress-induced feeding suppression in neonatal chicks.Intracerebroventricular administration of corticotropin-releasing hormone (CRH) or arginine vasotocin (AVT) antagonist diminished heat stress-induced suppression of feed intake in neonatal chicks. In addition, heat stress elicited the expression of c-Fos, the index gene of neuronal activation, in the preoptic and paraventricular regions of the hypothalamus. These data suggest that heat stress activates CRH and AVT neurons in the paraventricular region to induce a variety of stress responses such as feeding suppression in the hypothalamus of neonatal chicks.

已知暴露于高环境温度会对动物生长产生负面影响。其中一个因素是热应激强烈抑制动物的摄食行为，其机制尚不清楚。因此，本研究的目的是阐明热应激引起的新生雏鸡摄食抑制的脑机制，脑室注射促肾上腺皮质激素释放激素（CRH）或精氨酸血管紧张素（AVT）拮抗剂可减轻热应激引起的新生雏鸡摄食抑制。此外，热应激引起的表达c-Fos，神经元激活的指标基因，在视前和室旁区的下丘脑。这些结果表明，热应激激活了室旁区CRH和AVT神经元，引起了新生雏鸡下丘脑的摄食抑制等多种应激反应。

项目成果

Effect of Short-Term Thermal Conditioning on Physiological and Behavioral Responses to Subsequent Acute Heat Exposure in Chicks

短期热调节对雏鸡随后急性热暴露的生理和行为反应的影响

• 发表时间: 2014
• 期刊: Journal of Poultry Science
• 影响因子: 1.5
• 作者: Tanizawa H.;Shiraishi J.-I.;Kawakami S.-I.;Tsudzuki M. and Bungo T.
• 通讯作者: Tsudzuki M. and Bungo T.

Age-Dependent Change of Tonic Immobility Response in Chicks of a Native Japanese Chicken breed, Tosa-Jidori

日本本土鸡品种土佐鸡雏鸡强直不动反应的年龄依赖性变化

• DOI: 10.2141/jpsa.0130018
• 发表时间: 2013
• 期刊: The Journal of Poultry Science
• 作者: Tanizawa H.;Shiraishi J.-I.;Kawakami S.-I.;Tsudzuki M. and Bungo T.
• 通讯作者: Tsudzuki M. and Bungo T.

Effect of high environmental temperature on egg production, serum lipoproteins and follicle steroid hormones in laying hens

高温环境对蛋鸡产蛋量、血清脂蛋白和卵泡类固醇激素的影响

• 发表时间: 2011
• 期刊: Journal of Poultry Science
• 影响因子: 1.5
• 作者: Yoshida N.;Fujita M.;Nakahara M.;Kuwahara T.;Kawakami S.-I. and Bungo T.
• 通讯作者: Kawakami S.-I. and Bungo T.

Comparison of Plasma Amino Acid Levels of Two Breeds of Japanese Native Chicken and a Commercial Layer Line

两种日本本土鸡和商业蛋鸡系血浆氨基酸水平的比较

• DOI: 10.3923/ijps.2013.90.93
• 发表时间: 2013
• 期刊: International Journal of Poultry Science
• 作者: Takawaki M;Tanizawa H;Nakasai E;Shiraishi J;Kawakami S;Oka T;Tsudzuki M and Bungo T.
• 通讯作者: Tsudzuki M and Bungo T.

副腎皮質刺激ホルモン放出ホルモンは暑熱環境下におけるニワトリヒナの摂食量減少に関与する

促肾上腺皮质激素释放激素与炎热条件下雏鸡食物摄入量的减少有关。

• 发表时间: 2013
• 作者: 河上眞一;林由里子;川井田恵子;豊後貴嗣
• 通讯作者: 豊後貴嗣