Study on the Proportion of Intravenously Administered Drugs Excreted into the Stomach in Forensic Autopsy Cases

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I demonstrated that: (1) in both basic therapeutic agents that were intravenously administered during the course of unsuccessful medical treatments and intravenously self-administered methamphetamine, a relatively good positive correlation was observed between the levels of those substances in the blood and stomach contents; (2) the average stomach content-to-blood ratio was 9.59 for basic agents, 0.38 for acidic agents and 16.1 for methamphetamine; (3) up to 10 mg of methamphetamine can accumulate in the stomach; and (4) the stomach-to-blood methamphetamine ratio is significantly affected by the particular mechanism of death. The stomach content-to-blood ratio for basic drugs may serve as a criterion for discriminating whether a drug was administered orally or intravenously.