A study of gene polymorphism related to drug-induced lung disease
A study of gene polymorphism related to drug-induced lung disease
批准号:
23591143
负责人:
KUBO Keishi
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013
中文摘要
在本研究中,我们调查了近年来呈增加趋势的药物性肺部疾病患者的遗传背景。考虑到药物性肺部疾病患者的基因多态性,以达到早期诊断的目的,基因多态性与疾病之间存在多重关系。展望未来,通过积累更多的病例和基因功能分析,可以更清楚地了解药物性肺损伤的临床情况。
英文摘要
In this study, we investigated genetic background in patients with drug-induced lung disease, which has displayed an increasing trend in recent years. Upon considering gene polymorphism in patients with drug-induced lung disease for the purpose of early diagnosis, there were multiple relationships between gene polymorphism and the disease. Going forward, by means of the accumulation of an additional number of cases and genetic functional analysis, an even clearer understanding of the clinical conditions of drug-induced lung damage can be expected.
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【内科診療にガイドラインを生かす】呼吸器疾患 薬剤性肺障害
[内科使用指南] 呼吸系统疾病、药物引起的肺部疾病
DOI:
--
发表时间:
2013
期刊:
Medicina
影响因子:
--
作者:
[Masahiro Ishizuka, Yasunari Miyazaki, Tomoya Tateishi, Haruhiko Furusawa, Kimitake Tsuchiya, Toshihide Fujie, Meiyo Tamaoka, Hiroyuki Sakashita, Yuki Sumi, Naohiko Inase., 花岡正幸]
通讯作者:
花岡正幸
【内科診療にガイドラインを生かす】呼吸器疾患薬剤性肺障害
[内科使用指南] 呼吸系统疾病和药物引起的肺部疾病
DOI:
--
发表时间:
2013
期刊:
Medicina
影响因子:
--
作者:
[杉浦久敏, 花岡正幸]
通讯作者:
花岡正幸
医師・薬剤師のための医薬品副作用ハンドブック
医生和药剂师药物副作用手册
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[竹本 恭彦, 葭山 稔]
通讯作者:
葭山 稔
特集薬剤性肺障害の手引き序~薬剤性肺障害の重要性~
专题:药物性肺损伤简介 - 药物性肺损伤的重要性 -
DOI:
--
发表时间:
2013
期刊:
アレルギー・免疫
影响因子:
--
作者:
[久保惠嗣, 花岡正幸]
通讯作者:
花岡正幸
抗リウマチ薬による薬剤性肺炎の臨床的特徴
抗风湿药物引起的药物性肺炎的临床特点
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[池田麻里子, 市山崇史, 立石一成, 横山俊樹, 牛木淳人, 漆畑一寿, 山本洋, 花岡正幸, 久保惠嗣]
通讯作者:
久保惠嗣
共 13 条
Analysis of Genetic Contribution in the Development of Early-onset Chronic Obstructive Pulmonary Disease
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批准号:18590843
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.44万
-
财政年份:2006
-
负责人:KUBO Keishi
-
依托单位:
PATHOPHYSIOLOGICAL MECHANISM AND INDIVIDUAL SUSCEPTIBILITY IN HIGH-ALTITUDE ILLNESS
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批准号:13470126
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.61万
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财政年份:2001
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负责人:KUBO Keishi
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依托单位:
Analysis of Genetic and Constitutional Factors for the Development of High-altitude Pulmonary Edema
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批准号:09470539
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.22万
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财政年份:1997
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负责人:KUBO Keishi
-
依托单位:
THE ROLE OF INTERLEUKIN,TUMOR NECROSIS FACTOR-ALPHA AND PROTEINASES IN THE DEVELOPMENT OF ACUTE LUNG INJURY IN SHEEP
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批准号:08457179
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$1.34万
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财政年份:1996
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负责人:KUBO Keishi
-
依托单位:
USEFULNESS OF LIQUID VENTILATION BY PERFLUOROCARBON IN EXEPIMENTAL MODEL OF ACUTELUNG INJURY
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批准号:06670606
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.15万
-
财政年份:1994
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负责人:KUBO Keishi
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依托单位:
THE ROLE OF NEUTROPHIL, MACROPHAGE AND NEUTROPHIL ELASTASE IN THE DEVELOPMENT OF ACUTE LUNG INJURY
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批准号:04670463
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.79万
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财政年份:1992
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负责人:KUBO Keishi
-
依托单位:
The Study to Clarify The Pathophysiology of Endotoxin-induced Lung Injury -Especially The Role of Tumor Necrosis Factor-
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批准号:02807079
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.79万
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财政年份:1990
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负责人:KUBO Keishi
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依托单位:
THE PULMONARY FUNCTION IN LUNG INJURY INDUCED BY SEVERAL CUSES IN AWAKE SHEEP
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批准号:63480209
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$3.9万
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财政年份:1988
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负责人:KUBO Keishi
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依托单位:
海外基金