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Analysis of the pathogenic mechanisms of subacute sclerosing panencephalitis by use of recombinant measles viruses, and its therapeutic application

Analysis of the pathogenic mechanisms of subacute sclerosing panencephalitis by use of recombinant measles viruses, and its therapeutic application
重组麻疹病毒分析亚急性硬化性全脑炎的致病机制及其治疗应用
批准号:
23591510
负责人:
AYATA Minoru
金额:
$3.24万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011-04-28 至 2016-03-31

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Remarkable similarity in genome nucleotide sequences between the Schwarz FF-8 and AIK-C measles virus vaccine strains and apparent nucleotide differences in the phosphoprotein gene.
Schwarz FF-8 和 AIK-C 麻疹病毒疫苗株之间的基因组核苷酸序列具有显着的相似性,并且磷蛋白基因中存在明显的核苷酸差异。
DOI: 10.1111/j.1348-0421.2011.00339.x
发表时间: 2011
期刊: Microbiology and Immunology
影响因子: 2.6
作者: [Ito C, Ohgimoto S, Kato S, Sharma LB, Ayata M, Komase K, Takeuchi K, Ihara T, Ogura H.]
通讯作者: Ogura H.
Determinants of neurovirulence of the Osaka-1 strain of measles virus derived from a case of subacute sclerosing panencephalitis.
源自亚急性硬化性全脑炎病例的麻疹病毒 Osaka-1 株神经毒力的决定因素。
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [M. Ayata, S. Ohgimoto, M. Kuwamura, M. Tanaka, K. Takeuchi, M. Takeda, H. Ogura]
通讯作者: H. Ogura
Biased hypermutation occurred frequently in a gene inserted into the IC323 recombinant measles virus during its persistence in the brains of nude mice
IC323重组麻疹病毒在裸鼠大脑中持续存在期间,插入IC323重组麻疹病毒的基因经常发生偏向超突变
DOI: 10.1016/j.virol.2014.05.035
发表时间: 2014
期刊: Virology
影响因子: 3.7
作者: [Otani S, Ayata M, Takeuchi K, Takeda M, Shintaku H, Ogura H]
通讯作者: Ogura H
DOI: 10.1016/j.virol.2015.10.004
发表时间: 2016-01-01
期刊: VIROLOGY
影响因子: 3.7
作者: [Ayata, Minoru, Tanaka, Miyuu, Ogura, Hisashi]
通讯作者: Ogura, Hisashi
Development of a novel treatment for neuroviral infections using an experimental measles virus infection system as a model
  • 批准号:
    16K09994
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.0万
  • 财政年份:
    2016
  • 负责人:
    AYATA Minoru
  • 依托单位:
Analysis of host cellular receptors used by measles viruses derived from subacute sclerosing panencephalitis
  • 批准号:
    19591216
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.83万
  • 财政年份:
    2007
  • 负责人:
    AYATA Minoru
  • 依托单位:
Molecular mechanism of the infection and propagation of measles virus that cause subacute sclerosing panencephalitis
  • 批准号:
    17591108
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.18万
  • 财政年份:
    2005
  • 负责人:
    AYATA Minoru
  • 依托单位:
Viral factors responsible for the neurovirulence of SSPE virus
  • 批准号:
    10670290
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $0.64万
  • 财政年份:
    1998
  • 负责人:
    AYATA Minoru
  • 依托单位:
海外基金