Investigation of the characteristics of auditory feedback control of speech and its neural mechanisms

本文提出了一种用开环系统精确估计语音听觉反馈控制响应特性的新方法。它涵盖了听觉伪反馈信号调制开始后从十到几百ms的潜伏期范围。语音基频（F0）的反馈增益的频率依赖性在控制中观察到，但在口吃的主题。F0的反馈特征由3个主成分组成，它们具有不同的频率，并随注意条件的不同而不同地被调制，第一共振峰（F1）对F1阶跃表现出补偿性或跟随性反应，但产生这种差异的具体条件尚待研究。通过功能磁共振成像和近红外光谱技术，对文字阅读的脑功能成像显示，口吃者和不口吃者的大脑激活模式及其对文字熟悉程度的依赖性存在差异。

A new method to accurately estimate the response characteristics of the auditory feedback control of speech has been developed with an open loop system. It covers the latency range from ten to more than several hundred ms after the onset of the modulation of auditory pseudo-feedback signals. The frequency dependence of the feedback gain of the voice fundamental frequency (F0) was observed in the control but not in the stuttering subjects. The feedback characteristics of F0 comprised 3 principal components with different latencies that were modulated differentially depending on attentional conditions.The first formant (F1) showed either compensating or following responses to F1 steps, while the specific conditions for the difference are to be studied. Functional brain imaging of word reading revealed a difference in the brain activation pattern and its dependence on word familiarity between the people who stutter and who do not, using both fMRI and NIRS (near infrared spectroscopy).