Investigation of the characteristics of auditory feedback control of speech and its neural mechanisms

提出了一种利用开环系统准确估计语音听觉反馈控制响应特性的新方法。它涵盖了听觉伪反馈信号调制开始后从十毫秒到几百毫秒以上的延迟范围。在对照组中观察到语音基频反馈增益(F0)的频率依赖性，而在口吃组中观察不到。F0的反馈特性由3个潜伏期不同的主成分组成，根据注意条件的不同进行不同的调制。第一共振峰(F1)对F1阶跃的反应表现为补偿或跟随反应，但这种差异的具体条件有待研究。使用功能磁共振成像和近红外光谱分析，单词阅读的大脑功能成像显示，口吃者和非口吃者的大脑激活模式及其对单词熟悉度的依赖程度存在差异。

A new method to accurately estimate the response characteristics of the auditory feedback control of speech has been developed with an open loop system. It covers the latency range from ten to more than several hundred ms after the onset of the modulation of auditory pseudo-feedback signals. The frequency dependence of the feedback gain of the voice fundamental frequency (F0) was observed in the control but not in the stuttering subjects. The feedback characteristics of F0 comprised 3 principal components with different latencies that were modulated differentially depending on attentional conditions.The first formant (F1) showed either compensating or following responses to F1 steps, while the specific conditions for the difference are to be studied. Functional brain imaging of word reading revealed a difference in the brain activation pattern and its dependence on word familiarity between the people who stutter and who do not, using both fMRI and NIRS (near infrared spectroscopy).