Development of phase sensitive radiography for human imaging by means of synchrotron radiation

开发同步辐射人体成像相敏放射线照相术

• 批准号: 12670895
• 负责人: MORI Koichi
• 金额: $ 2.3万
• 依托单位: IBARAKI PREFECTURAL UNIVERSITY OF HEALTH SCIENCES
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2000
• 资助国家: 日本
• 起止时间: 2000 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12670895/
• 关键词: Synchrotron Radiation; Radiography; Refraction Contrast; Wooden Foreign Body; Small Fracture; Calcification; Spatial Coherence; Reduction of Exposure Dose; 被曝線量の軽減; 位相コントラスト; 骨画像; フレネル回折; 干渉性

Refraction contrast imaging of the fine structures of the ribs of a pig and a specimen of human osteosarcoma utilizing the spatial coherence of synchrotron X-rays was successfully performed with an incident X-ray energy of 30 keV at KEK.PF and SPring-8. The image contrast appearing at the periphery of trabecular bone, small calcification and small fractures is caused by the phase shift of the X-rays at the boundary of these objects that have different X-ray refractive indices. The image was recorded on mammography film without an intensifying screen. Comparison of the image contrast using different sample-to-film distances, Z, such as Z=5 m and Z=0 m, showed that the former images were always more informative, i.e. better in resolution and /or image contrast when imaging of trabecular bone, bone marrow and small fractures in compact bone, and for imaging of cartilage.Refraction contrast imaging of a pig head with penetration of wooden foreign body in his oral cavity utilizing the spatial coherence of synchrotron X-rays was successfully performed with an incident X-ray energy of 35 keV at BL20B2 of SPring-8. The image was recorded on mammography film with an intensifying screen. Comparison of the image contrast using different sample-to-film distances such as Z=5 m and Z=0 m, showed that the former images were always more informative, i.e. the wooden foreign body could be detected only by the refraction contrast imaging.Radiography using synchrotron X-rays for phase objects should be a powerful tool for diagnosis in orthopedics and wooden foreign body imaging.

利用同步辐射X射线的空间相干性，成功地进行了猪肋骨和人骨肉瘤标本的精细结构的折射衬度成像，入射X射线能量为30 keV，在KEK.PF和SPring-8。在骨小梁、小钙化和小骨折的周边出现的图像对比度是由在具有不同X射线折射率的这些对象的边界处的X射线的相移引起的。图像记录在没有增感屏的乳房X线摄影胶片上。使用不同的样品到胶片距离Z（例如Z=5 m和Z=0 m）的图像对比度的比较表明，当对骨小梁、骨髓和密质骨中的小骨折进行成像时，前一种图像总是信息量更大，即分辨率和/或图像对比度更好，利用同步辐射X射线空间相干性对猪口腔内木质异物穿透头部的折射衬度成像进行了研究。在SPring-8的BL 20 B2处，用35 keV的入射X射线能量成功地进行了X射线。图像被记录在带有增感屏的乳房X光检查胶片上。通过比较Z=5 m和Z=0 m两种不同样品-胶片距离下的图像对比度，发现前者的图像信息量更大，即只有折射对比度成像才能检测到木质异物，同步辐射X射线相位物体摄影术应成为骨科和木质异物成像诊断的有力工具。

项目成果

K.Mori, et al.: "Development of Radiological Osteometry by Means of Synchrotron X-ray Phase Contrast"SPring-8 User Experiment Report. 9(2002A). 125 (2002)

K.Mori 等人：“通过同步加速器 X 射线相位对比进行放射骨测量的发展”SPring-8 用户实验报告。

Hitoshi Sato: "Phase Contrast Imaging for Mammography Using Synchrotron X-rays"M.J.Ibaraki P.H.. 20-2. 73-82 (2002)

Hitoshi Sato：“使用同步加速器 X 射线进行乳房 X 射线摄影的相衬成像”M.J.Ibaraki P.H.. 20-2。

K.Mori, et al.: "First Observation of a Wooden Foreign Body in Soft Palate by Means of Synchrotron X-ray Refraction Contrast"Jpn.J.Appl.Phys.. 41・8. 5490-5491 (2002)

K.Mori等人：“通过同步加速器X射线折射对比首次观察软腭中的木制异物”Jpn.J.Appl.Phys.. 41・8（2002）。

H.Sato, K.Mori, et al.: "Phase Contrast Imaging for Mammography Using Synchrotron X-rays"M.J.Ibaraki P.H.. 20・2. 73-82 (2002)

H.Sato、K.Mori 等：“使用同步加速器 X 射线进行乳房 X 射线摄影的相位对比成像”M.J.Ibaraki P.H.. 20・2 (2002)。

K.Mori,N.Shikano,H.Soto,K.Hyodo,M.Ando et al.: "Development of a novel radiography for visualization of fracture line by means of synchrotron x-ray phase contrast"Book of abstracts of the 7 th international conference on synchrotron radiation instrumentat

K.Mori、N.Shikano、H.Soto、K.Hyodo、M.Ando 等人：“通过同步加速器 X 射线相衬可视化骨折线的新颖射线照相术的开发”7 期摘要书