Development of the multipurpose adhesive system using Drug Delivery for Improved Direct pulp capping, Pulpotomy, and Periodontal treatment

本研究的目的是利用可见光诱导的可交联蛋白和磷酸化普鲁兰开发一种多用途的生物胶粘剂体系。这些发现证实了以下几点。磷酸化普鲁兰基复合材料与牙本质黏附，具有较高的生物相容性。可见光诱导交联明胶与牙本质黏附，细胞毒性低。由此可见，光诱导交联明胶和磷酸化普鲁兰可作为生物可降解骨、牙再生和重建胶粘剂的关键材料。

The purpose of this study is to develop a multi-purpose bio-adhesive system by the visible light-induced crosslinkable geratin and phosphorylated pullulan. The following things were confirmed from these findings. Phosphorylated pullulan-based composite is adhesive to dentin and possesses high biocompatibility. The visible light-induced crosslinkable gelatin is adhesive to dentin and low cellular toxicity. It was suggested that the visible light-induced crosslinkable gelatin and phosphorylated pullulan can be used as key materials of biodegradable adhesives for regeneration and reconstruction of bone and tooth.