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Anesthetic effects decreased or increased by the novel pharmacodynamic interactions on biomembrane lipids

Anesthetic effects decreased or increased by the novel pharmacodynamic interactions on biomembrane lipids
通过对生物膜脂质的新型药效相互作用减少或增加麻醉效果
批准号:
23593005
负责人:
TSUCHIYA Hironori
金额:
$3.16万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2014

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会议论文
Plant Components Exhibit Pharmacological Activities and Drug Interactions by Acting on Lipid Membranes
植物成分通过作用于脂膜表现出药理活性和药物相互作用
DOI: --
发表时间: 2012
期刊: Pharmacognosy Communications
影响因子: --
作者: [Hironori Tsuchiya, Maki Mizogami]
通讯作者: Maki Mizogami
Increasing Membrane Interactions of Local Anaesthetics as Hypothetic Mechanism for Their Cardiotoxicity Enhanced by Myocardial Ischaemia
局部麻醉药的膜相互作用增加作为心肌缺血增强其心脏毒性的假设机制
DOI: 10.1111/j.1742-7843.2012.00909.x
发表时间: 2012
期刊: Basic and Clinical Pharmacology and Toxicology
影响因子: 3.1
作者: [Hironori Tsuchiya, Maki Mizogami and Kenji Shigemi]
通讯作者: Maki Mizogami and Kenji Shigemi
STEREOSELECTIVE MEMBRANE INTERACTION OF LOCAL ANESTHETICS AT CARDIOTOXICALLY RELEVANT CONCENTRATIONS: MEMBRANE CHOLESTEROL DETERMINES THE STEREOSELECTIVITY
局部麻醉剂在心脏毒性相关浓度下的立体选择性膜相互作用:膜胆固醇决定立体选择性
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [M. Mizogami, H. Tsuchiya, T. Ueno, K. Takakura]
通讯作者: K. Takakura
心毒性をもつ局所麻酔薬の機序的膜相互作用は心筋虚血様酸性条件で増強される
在心肌缺血样酸性条件下,心脏毒性局麻药的机械膜相互作用增强
DOI: --
发表时间:
期刊:
影响因子: --
作者: [松木 悠佳, 溝上 真樹, 重見 研司, 土屋 博紀]
通讯作者: 土屋 博紀
16
    Novel pharmacodynamic interactions of anesthetics: Anesthetic effects decreased or increased by herbs and supplements in the perioperative period
    • 批准号:
      26463078
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.08万
    • 财政年份:
      2014
    • 负责人:
      TSUCHIYA Hironori
    • 依托单位:
    Reverification of the mechanistic membrane effects of anesthetics : Interactions with biomembrane rafts and specific membrane lipids
    • 批准号:
      20592381
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.83万
    • 财政年份:
      2008
    • 负责人:
      TSUCHIYA Hironori
    • 依托单位:
    The interaction between Mammalian Alkaloids and Anesthetics : Anesthetic Tolerance Associated with Alcohol Drinking and Prediction by Hair Analysis
    • 批准号:
      15592145
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.79万
    • 财政年份:
      2003
    • 负责人:
      TSUCHIYA Hironori
    • 依托单位:
    Phytopreventive and Phytotherapeutic Application to Dentistry - Anti-dental caries and anti-periodontal disease activity, and oral retentivity after application of edible phytochemical flavonoids and alkaloids -
    • 批准号:
      09671911
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $0.7万
    • 财政年份:
      1997
    • 负责人:
      TSUCHIYA Hironori
    • 依托单位:
    海外基金