Development of novel screening method based on the visualization of permeability distribution of cell layer

化学图像传感器是一种能够直观地显示电解液中离子分布的传感器。在这项研究中，一个便携式的化学成像系统，这是小，便宜和工作的独立。此外，还实现了细胞层电阻率分布的可视化。这预示着基于电学特性的紧密结可视化将成为可能。基于这一结果，也可以预期新的筛选试验，以评估化学品对细胞的影响。

Chemical image sensor is a sensor which can visualize the ion distribution in the electrolyte. In this study, a portable chemical imaging system which is small, inexpensive and working stand-alone was developed. In addition to that, the visualization of resistivity distribution of cultured-cell layer was succeeded. It indicates that the visualization of the tight-junction based on electrical property will be possible in the future. Based on this result, novel screening assay to evaluate the influence of chemicals to the cells can be also expected.