Elucidation of the contribution of lymphatic transport to the intestinal absorption of various food factors

阐明淋巴运输对肠道吸收各种食物因子的贡献

• 批准号: 23617032
• 负责人: MUROTA Kaeko
• 金额: $ 3.49万
• 依托单位: Kinki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23617032/
• 关键词: 腸管吸収; リンパ系輸送; カイロミクロン; フラボノイド; ビタミンE; プロビタミンAカロテノイド; リンパ輸送; ヘスペレチン; プロビタミンA; ナノ粒子; メチル水銀; ケルセチン配糖体; Caco-2; CD36

We investigated the contribution of lymphatic transport to the intestinal absorption of various food factors, including vitamin E, carotenoids and flavonoids. Lymphatic transport level of highly hydrophobic vitamins was effectively enhanced when they were solubilized in the intestinal fluid, whereas a quercetin glucoside, a major flavonoid glycoside, was less absorbed when administrated with fatty acids simultaneously. It was also suggested that a relatively hydrophobic methoxyflavonoid was transported in the lymph at the higher level than quercetin.

我们研究了淋巴转运对肠道吸收各种食物因子的贡献，包括维生素E、类胡萝卜素和类黄酮。淋巴转运水平的高度疏水性的维生素被有效地增强时，它们被溶解在肠液中，而槲皮素葡萄糖苷，一个主要的黄酮苷，被吸收较少时，同时与脂肪酸。有人还建议，一个相对疏水的甲氧基黄酮在淋巴中的运输水平高于槲皮素。

项目成果

Effect of lipids on the direct absorption of methyl mercury by lymph and blood.

脂质对淋巴和血液直接吸收甲基汞的影响。

• 发表时间: 2014
• 期刊: Science and Technology
• 作者: Takagi M;Ukibe D;Murota K;Minami T.
• 通讯作者: Minami T.

Contribution of lymphatic transport to the intestinal absorption of food components

淋巴运输对肠道吸收食物成分的贡献

• 发表时间: 2011
• 作者: Takayama M;Arai Y;Sasaki S;Hashimoto M;Shimizu K;Abe Y;Hirose N;海野けい子;Murota K
• 通讯作者: Murota K

Effect of lipids on the direct absorption of methyl mercury by lymph and blood

脂质对淋巴和血液直接吸收甲基汞的影响

• 发表时间: 2014
• 期刊: Science and Technology
• 作者: Takagi M;Ukibe D;Murota K;Minami T
• 通讯作者: Minami T

ラットにおけるプロビタミンAカロテノイドの腸管吸収代謝動態

维生素原A类胡萝卜素在大鼠体内的肠道吸收和代谢动力学

• 发表时间: 2012
• 作者: 藤田琴子;室田佳恵子
• 通讯作者: 室田佳恵子