Influences of plant flavonoids on body functions and basical research for evaluation of functional foods

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In the present study, the effects of plant flavonoids on catecholamine synthesis and secretion were investigated in cultured bovine adrenal medullary cells. Nobiletin, a citrus plomethoxy flavoe, and daidzein, a soy isoflavone, stimulated catecholamine synthesis and/or secretion while they inhibited catecholamine synthesis and secretion induced by acetylcholine. The present results suggest that some plant flavonoids suppress the hyperactive catecholamine system induced by a strong stress or emotional excitation which evokes the secretion of acetylcholine from the slpanchnic nerves and stimulates a massive release of catecholamines from adrenal medulla. These flavonoid foods may an anti-stress effect.