Distinguish malignant melanomas and benign nevi based on the blood flow velocity of new blood vessels in tumor with blood flow velocity 3D images

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We intend to develop a laser Doppler velocimetry (LDV) system for in-vivo imaging that can measure blood flow velocity, that can generate tomograph of blood vessels with information in the depth direction and that has a high spatial resolution to enable individual microvessels. We measured microvessels of an experimental mouse, and succeeded in imaging the blood flow velocity in microvessels as 2 or 3 dimensional images. Finally, we demonstrate that using MLDV of blood vessels is useful for diagnosing malignant melanomas by comparison with visual diagnosis by dermoscopy.