One-pot preparation of dendrimer-gold nanohybrids with controlled photothermal property and their application to cancer therapy
One-pot preparation of dendrimer-gold nanohybrids with controlled photothermal property and their application to cancer therapy
批准号:
23650293
负责人:
KONO Kenji
金额:
$2.33万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
In this study, we attempted to develop dendrimer-gold nanorod hybrids with controlled size and photothermal property. The hybrids with small size and high photothermal property were prepared by formation of gold nanorod in the presence of polyethyelen glycol-modified polyamidoamine dendrimers with disulfide bond at the core. Cancer cells taking up the hybrids were killed effectively under near infrared light irradiation and hence these hybrids might be potentially useful as a nanodevice for photothermal therapy for cancer.
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Preparation of Stimuli-Responsive Dendrimer-Gold Nanoparticle Hybdirs for Biomedical Applications
用于生物医学应用的刺激响应性树枝状聚合物-金纳米颗粒杂化物的制备
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[K. Kono, K. Takeda, E. Yuba, A. Harada]
通讯作者:
A. Harada
Design of a novel drug carrier with photo-responsive properties: drug-encapsulated and alkanethiol-modified gold nanoparticle-loaded PEGylated dendrimer
具有光响应特性的新型药物载体的设计:药物封装和烷硫醇修饰的金纳米颗粒负载聚乙二醇化树枝状聚合物
DOI:
--
发表时间:
期刊:
Chem. Lett
影响因子:
--
作者:
[C. Kojima, H. Kawabata, A. Harada, H. Horinaka, K. Kono]
通讯作者:
K. Kono
Design of Stimuli-sensitive Dendrimers, Dendrimer-gold Hybrids and Dendrimer-based Assemblies for Biomedical Applications
用于生物医学应用的刺激敏感树枝状聚合物、树枝状聚合物-金杂化物和基于树枝状聚合物的组件的设计
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Hirohito Mori, et al, K. Kono]
通讯作者:
K. Kono
金ナノロッドコア PEG 修飾 PAMAM デンドリマーの作製と光発熱特性
金纳米棒核PEG修饰PAMAM树枝状聚合物的制备及光热性能
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[武田啓志, 弓場英司, 原田敦史, 河野健司]
通讯作者:
河野健司
刺激応答性ナノキャリアの開発
刺激响应纳米载体的开发
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Matsuda T, Kumahara H, Obara S, Kiyonaga A, Shindo M, Tanaka H., 河野健司]
通讯作者:
河野健司
共 21 条
Power-Saving Virtual Machine Scheduling for Many-Core CPUs in Cloud Environments
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批准号:23500050
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.24万
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财政年份:2011
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负责人:KONO Kenji
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依托单位:
Development of multifunctional nano-vesicles having target accumulation, temperature-response, and imaging abilities
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批准号:19200040
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$30.28万
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财政年份:2007
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负责人:KONO Kenji
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依托单位:
Preparation of efficient gene vectors with multi functions
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批准号:16300159
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.34万
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财政年份:2004
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负责人:KONO Kenji
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依托单位:
Development of novel synthetic gene delivery systems with an ability to fuse with cells
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批准号:13558115
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.04万
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财政年份:2001
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负责人:KONO Kenji
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依托单位:
A Comprehensive Study on the Plays of St. John Ervine as a Playwright
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批准号:13610599
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$0.32万
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财政年份:2001
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负责人:KONO Kenji
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依托单位:
Design of novel nanocapsules with target-specificity using dendrimers
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批准号:12680839
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.37万
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财政年份:2000
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负责人:KONO Kenji
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依托单位:
海外基金