Development of multifunctional nano-vesicles having target accumulation, temperature-response, and imaging abilities
Development of multifunctional nano-vesicles having target accumulation, temperature-response, and imaging abilities
批准号:
19200040
负责人:
KONO Kenji
金额:
$30.28万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2010
中文摘要
在这项研究中,我们成功地开发了一种新型的多功能纳米囊泡,具有肿瘤积聚,温度响应性药物释放和MRI可检测功能。使用多功能纳米囊泡实现了高效的肿瘤化疗。结果可能导致个性化化疗的发展,为个体患者提供最佳化疗。
英文摘要
In this study, we successfully developed a new type of multifunctional nanovesicles that have tumor-accumulating, temperature-responsive drug releasing, and MRI-detectable functions. Highly efficient tumor chemotherapy was achieved using the multifunctional nanovesicles. Results might lead to the development of personalized chemotherapy that provides best chemotherapy optimized to individual patient.
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Thermosensitive vesicles from PAMAM dendron-based lipids
来自 PAMAM 树枝状脂质的热敏囊泡
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[K.Kono, Y.Hiranaka, E.Yuba, A.Harada]
通讯作者:
A.Harada
DOI:
10.1021/bc8001503
发表时间:
2008-11-01
期刊:
BIOCONJUGATE CHEMISTRY
影响因子:
4.7
作者:
[Kojima, Chic, Toi, Yoko, Kono, Kenji]
通讯作者:
Kono, Kenji
DOI:
10.1021/la0700826
发表时间:
2007-05-08
期刊:
LANGMUIR
影响因子:
3.9
作者:
[Haba, Yasuhiro, Kojima, Chie, Kono, Kenji]
通讯作者:
Kono, Kenji
Modification of liposome surface with pH-responsive polyampholytes for the controlled-release of drugs
用 pH 响应型聚两性电解质修饰脂质体表面以实现药物控释
DOI:
--
发表时间:
2009
期刊:
Research On Chemical Intermediates 35巻
影响因子:
--
作者:
[L.T.Ng, E.Yuba, K.Kono]
通讯作者:
K.Kono
DOI:
10.1007/s11164-009-0083-z
发表时间:
2009-10
期刊:
Research on Chemical Intermediates
影响因子:
3.3
作者:
[Toshinari Takahashi;E. Yuba;C. Kojima;Atsushi Harada;K. Kono]
通讯作者:
Toshinari Takahashi;E. Yuba;C. Kojima;Atsushi Harada;K. Kono
共 106 条
Power-Saving Virtual Machine Scheduling for Many-Core CPUs in Cloud Environments
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批准号:23500050
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.24万
-
财政年份:2011
-
负责人:KONO Kenji
-
依托单位:
One-pot preparation of dendrimer-gold nanohybrids with controlled photothermal property and their application to cancer therapy
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批准号:23650293
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
-
财政年份:2011
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负责人:KONO Kenji
-
依托单位:
Preparation of efficient gene vectors with multi functions
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批准号:16300159
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.34万
-
财政年份:2004
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负责人:KONO Kenji
-
依托单位:
Development of novel synthetic gene delivery systems with an ability to fuse with cells
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批准号:13558115
-
项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.04万
-
财政年份:2001
-
负责人:KONO Kenji
-
依托单位:
A Comprehensive Study on the Plays of St. John Ervine as a Playwright
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批准号:13610599
-
项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$0.32万
-
财政年份:2001
-
负责人:KONO Kenji
-
依托单位:
Design of novel nanocapsules with target-specificity using dendrimers
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批准号:12680839
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.37万
-
财政年份:2000
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负责人:KONO Kenji
-
依托单位:
海外基金