课题基金 / 基金详情

Development of multifunctional nano-vesicles having target accumulation, temperature-response, and imaging abilities

Development of multifunctional nano-vesicles having target accumulation, temperature-response, and imaging abilities
开发具有目标积累、温度响应和成像能力的多功能纳米囊泡
批准号:
19200040
负责人:
KONO Kenji
金额:
$30.28万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2010

项目摘要

项目成果

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中文摘要
翻译
在这项研究中,我们成功地开发了一种新型的多功能纳米微囊,它具有肿瘤累积、温度响应性药物释放和MRI可检测的功能。利用多功能纳米微囊实现了高效的肿瘤化疗。结果可能导致个性化化疗的发展,为个体患者提供最佳的化疗方案。
英文摘要
In this study, we successfully developed a new type of multifunctional nanovesicles that have tumor-accumulating, temperature-responsive drug releasing, and MRI-detectable functions. Highly efficient tumor chemotherapy was achieved using the multifunctional nanovesicles. Results might lead to the development of personalized chemotherapy that provides best chemotherapy optimized to individual patient.
期刊论文(113)
专著(0)
科研奖励(0)
会议论文
Thermosensitive vesicles from PAMAM dendron-based lipids
来自 PAMAM 树枝状脂质的热敏囊泡
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [K.Kono, Y.Hiranaka, E.Yuba, A.Harada]
通讯作者: A.Harada
DOI: 10.1021/bc8001503
发表时间: 2008-11-01
期刊: BIOCONJUGATE CHEMISTRY
影响因子: 4.7
作者: [Kojima, Chic, Toi, Yoko, Kono, Kenji]
通讯作者: Kono, Kenji
DOI: 10.1021/la0700826
发表时间: 2007-05-08
期刊: LANGMUIR
影响因子: 3.9
作者: [Haba, Yasuhiro, Kojima, Chie, Kono, Kenji]
通讯作者: Kono, Kenji
Modification of liposome surface with pH-responsive polyampholytes for the controlled-release of drugs
用 pH 响应型聚两性电解质修饰脂质体表面以实现药物控释
DOI: --
发表时间: 2009
期刊: Research On Chemical Intermediates 35巻
影响因子: --
作者: [L.T.Ng, E.Yuba, K.Kono]
通讯作者: K.Kono
106
    Power-Saving Virtual Machine Scheduling for Many-Core CPUs in Cloud Environments
    • 批准号:
      23500050
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.24万
    • 财政年份:
      2011
    • 负责人:
      KONO Kenji
    • 依托单位:
    One-pot preparation of dendrimer-gold nanohybrids with controlled photothermal property and their application to cancer therapy
    • 批准号:
      23650293
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.33万
    • 财政年份:
      2011
    • 负责人:
      KONO Kenji
    • 依托单位:
    Preparation of efficient gene vectors with multi functions
    • 批准号:
      16300159
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $9.34万
    • 财政年份:
      2004
    • 负责人:
      KONO Kenji
    • 依托单位:
    Development of novel synthetic gene delivery systems with an ability to fuse with cells
    • 批准号:
      13558115
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $7.04万
    • 财政年份:
      2001
    • 负责人:
      KONO Kenji
    • 依托单位:
    海外基金