Neuroprotective effects of focal brain cooling on acute cerebrovascular disease
Neuroprotective effects of focal brain cooling on acute cerebrovascular disease
批准号:
23650326
负责人:
INOUE Takao
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
We investigated whether FBC has a favorable effect on focal cerebral ischemia (FCI). Under general anesthesia, a small burr-hole was made and FCI was induced in the rat primary sensorimotor area (SI-MI) using photothrombosis. After that, FBC was performed. We report the novel finding that epileptiform discharges were suppressed in the ischemic border, the infarct area was reduced and neurobehaviour was preserved by FBC.
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Challenges and Opportunities for development of a focal cooling device for intractable epilepsy
难治性癫痫局灶冷却装置开发的挑战与机遇
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Takao Inoue, Masami Fujii, Tatsuji Tokiwa, Yuichi Maruta, Hiroyuki Kida, Yeting He, Toshitaka Yamakawa, Hirochika Imoto, Sadahiro Nomura, Kenichi Hirano, Masanori Niiyama, Hiromi Yamazaki, Yuji Owada, Takeshi Yamakawa, Michiyasu Suzuki]
通讯作者:
Michiyasu Suzuki
Development of a focal cerebral cooling system for the treatment of intractable epilepsy An experimental study in cats and non-human primates
开发用于治疗顽固性癫痫的局灶性脑冷却系统在猫和非人类灵长类动物中的实验研究
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Takao Inoue, Masami Fujii, Yeting He, Yuichi Maruta, Hiroyuki Kida, Sadahiro Nomura, Tatsuji Tokiwao, Toshitaka Yamakawa, Kenichi Hirano, Masanori Niiyama, Hiromi Yamazaki, Takeshi Yamakawa, Michiyasu Suzuki]
通讯作者:
Michiyasu Suzuki
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Masami Fujii, Takao Inoue, Yeting He, Hirochika Imoto, Nobuyuki Tanaka, T Oku, Yuichi Maruta, Hiroyasu Koizumi, Sadahiro Nomura, Yuji Owada, Takashi Saito, Toshitaka Yamakawa, Tatsuji Tatsuji Tokiwa, Takeshi Yamakawa, Michiyasu Suzuki]
通讯作者:
Michiyasu Suzuki
霊長類を用いた痙攣誘発てんかんモデルに対する局所脳冷却と運動機能への抑制効果
灵长类动物惊厥诱发癫痫模型中局部脑冷却和对运动功能的抑制作用
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[賀業霆, 井上貴雄, 丸田雄一, 木田浩之, 岡史朗, 野村貞宏, 藤井正美, 大和田祐二, 山川烈, 鈴木倫保, 賀業霆,藤井正美,井上貴雄,野村貞宏,木田裕之,丸田雄一,国次一郎,山川烈,鈴木倫保, 井上貴雄,藤井正美,木田裕之,山川俊貴,丸田雄一,賀業霆,常盤達司,野村貞宏,大和田祐二,山川烈,鈴木倫保]
通讯作者:
井上貴雄,藤井正美,木田裕之,山川俊貴,丸田雄一,賀業霆,常盤達司,野村貞宏,大和田祐二,山川烈,鈴木倫保
機能神経外科の新たなアプローチ:Thermal neuromodulation
功能神经外科的新方法:热神经调节
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[藤井正美, 井上貴雄, 賀業霆, 丸田雄一, 井本浩哉, 田中信宏, 奥高行, 藤岡裕士, 米田浩, 小泉博靖, 野村貞宏, 鈴木倫保, 山川烈]
通讯作者:
山川烈
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