Study of mechanism of a rapid and profound transition in glucose concentration during the Pringle maneuver

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The Pringle maneuver is performed in hepatectomy due to reduce hemorrhage. Our previous study using a continuous blood glucose monitoring revealed that liver ischemia/reperfusion causes a rapid and profound transition in glucose concentration. Our study showed that glucose release from the hepatic vein and sinusoid leads to a rapid elevation in systemic blood glucose levels after liver ischemia/reperfusion. Furthermore, we investigated whether iatrogenic blood glucose variation cause inflammation.